Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정민성 | - |
dc.date.accessioned | 2019-11-21T07:54:01Z | - |
dc.date.available | 2019-11-21T07:54:01Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE, v. 32, no. 6, page. 1031-1037 | en_US |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://jkms.org/DOIx.php?id=10.3346/jkms.2017.32.6.1031 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113323 | - |
dc.description.abstract | The purpose of this study was to investigate the correlations between tumor-to-background ratio (TBR) obtained from breast-specific gamma imaging (BSGI) and the prognostic factors of breast cancer. Sixty-seven patients with invasive ductal carcinoma who underwent preoperative BSGI were enrolled. The BSGI images were visually scored from 1 to 5 according to a breast imaging reporting and data system (BIRADS). The TBR results obtained from positive BSGI images were compared according to the following prognostic factors: tumor size; axillary lymph node metastasis; nuclear grade (NG); histologic grade (HG); subtype; Ki-67; and the expression profile of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Among 67 images, 60 were classified as a positive finding (sensitivity 89.6%). A higher TBR value was significantly correlated with tumor size >= 2 cm (P= 0.001), axillary lymph node metastasis (P= 0.007), high HG (P= 0.029), negative PR status (P= 0.036), and Ki67 >= 14% (P= 0.007). The TBR showed a significant difference between the luminal A and non-luminal A subtypes (P= 0.007). On multivariate analysis, TBR had a high correlation with tumor size >= 2 cm, axillary lymph node metastasis, and negative PR status (P= 0.003, 0.048, and 0.030, respectively). A high TBR on BSGI was significantly correlated with poor prognostic factors of breast cancer. Luminal A subtype, a breast cancer subtype with more favorable prognosis, was associated with a low TBR on BSGI. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | en_US |
dc.subject | Breast Cancer | en_US |
dc.subject | Gamma Camera Imaging | en_US |
dc.subject | Tc-99m-sestaMIBI | en_US |
dc.title | Correlations between Tumor to Background Ratio on Breast-Specific Gamma Imaging and Prognostic Factors in Breast Cancer | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 32 | - |
dc.identifier.doi | 10.3346/jkms.2017.32.6.1031 | - |
dc.relation.page | 1031-1037 | - |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.contributor.googleauthor | Lee, Soo Jin | - |
dc.contributor.googleauthor | Choi, Yun Young | - |
dc.contributor.googleauthor | Kim, Chanwoo | - |
dc.contributor.googleauthor | Chung, Min Sung | - |
dc.relation.code | 2017002851 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | bovie | - |
dc.identifier.orcid | http://orcid.org/0000-0001-5086-3718 | - |
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