Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박용순 | - |
dc.date.accessioned | 2019-11-21T01:30:39Z | - |
dc.date.available | 2019-11-21T01:30:39Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.citation | NUTRIENTS, v. 9, no. 4, Article no. 399 | en_US |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | https://www.mdpi.com/2072-6643/9/4/399 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113018 | - |
dc.description.abstract | Protein-energy wasting (PEW) is associated with mortality in patients with end-stage renal disease (ESRD) on maintenance hemodialysis. The correct diagnosis of PEW is extremely important in order to predict clinical outcomes. However, it is unclear which parameters should be used to diagnose PEW. Therefore, this retrospective observational study investigated the relationship between mortality and nutritional parameters in ESRD patients on maintenance hemodialysis. A total of 144 patients were enrolled. Nutritional parameters, including body mass index, serum albumin, dietary intake, normalized protein catabolic rate (nPCR), and malnutrition inflammation score (MIS), were measured at baseline. Fifty-three patients died during the study. Survivors had significantly higher nPCR (1.10 +/- 0.24 g/kg/day vs. 1.01 +/- 0.21 g/kg/day; p = 0.048), energy intake (26.7 +/- 5.8 kcal/kg vs. 24.3 +/- 4.2 kcal/kg; p = 0.009) and protein intake (0.91 +/- 0.21 g/kg vs. 0.82 +/- 0.24 g/kg; p = 0.020), and lower MIS (5.2 +/- 2.3 vs. 6.1 +/- 2.1, p = 0.039). In multivariable analysis, energy intake <25 kcal/kg (HR 1.860, 95% CI 1.018-3.399; p = 0.044) and MIS > 5 (HR 2.146, 95% CI 1.173-3.928; p = 0.013) were independent variables associated with all-cause mortality. These results suggest that higher MIS and lower energy intake are harmful to ESRD patients on maintenance hemodialysis. Optimal energy intake could reduce mortality in these patients. | en_US |
dc.description.sponsorship | This research was supported by the Senior-friendly Product R&amp;D program through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health &amp; Welfare, Republic of Korea (Grant No.: HI15C3207). We thank Seunghee Baek, statistician, Department of Medical Statistics, Asan Medical Center for statistical review. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | MDPI | en_US |
dc.subject | protein energy wasting | en_US |
dc.subject | mortality | en_US |
dc.subject | hemodialysis | en_US |
dc.subject | nutritional parameters | en_US |
dc.title | Nutritional Status Predicts 10-Year Mortality in Patients with End-Stage Renal Disease on Hemodialysis | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 9 | - |
dc.identifier.doi | 10.3390/nu9040399 | - |
dc.relation.page | 9-9 | - |
dc.relation.journal | NUTRIENTS | - |
dc.contributor.googleauthor | Kang SS | - |
dc.contributor.googleauthor | Chang J | - |
dc.contributor.googleauthor | Park Y | - |
dc.contributor.googleauthor | Kang, Shin Sook | - |
dc.contributor.googleauthor | Chang, JaiWon | - |
dc.contributor.googleauthor | Park, Yongsoon | - |
dc.relation.code | 2017007641 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF HUMAN ECOLOGY[S] | - |
dc.sector.department | DEPARTMENT OF FOOD & NUTRITION | - |
dc.identifier.pid | yongsoon | - |
dc.identifier.researcherID | E-6968-2017 | - |
dc.identifier.orcid | http://orcid.org/0000-0001-5110-5716 | - |
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