36 0

Polyelectrolyte/silica-layered hydrogel microcapsules as vehicles with remarkable shell impermeability

Title
Polyelectrolyte/silica-layered hydrogel microcapsules as vehicles with remarkable shell impermeability
Author
이영복
Keywords
Microcapsules; Microfluidics; LbL deposition; Shell impermeability
Issue Date
2017-02
Publisher
ELSEVIER SCIENCE INC
Citation
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v. 46, page. 192-198
Abstract
This paper introduces a practically useful approach for fabrication of hydrogel microcapsules layered with a mechanically robust polyelectrolyte/silica thin shell. For this, monodisperse negatively charged hydrogel microparticles were fabricated combining the microfluidic technique and subsequent photo-polymerization. Then, alternate polyelectrolyte layers were generated onto the microparticles by using the layer-by-layer deposition. In the final stage, reduction of silicate on the polyelectrolyte layer was conducted to form a silica layer on the outer most layer of the shell. Uniform covering of the periphery of the hydrogel microparticles with the hybrid shell layer was confirmed by SEM and EDX analyses as well as by improved structural shell resistance to osmolality. The thickness of the shell layer was detected by approximately one micrometer. Finally, we demonstrated that the polyelectrolyte/silica hybrid shell showed remarkably low permeability against small molecules, which allows us to explore microcapsule applications toward complete segregation and stabilization of water-soluble active molecules. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S1226086X16304099?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/112668
ISSN
1226-086X; 1876-794X
DOI
10.1016/j.jiec.2016.10.030
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE