Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 장일훈 | - |
dc.date.accessioned | 2019-10-31T02:10:42Z | - |
dc.date.available | 2019-10-31T02:10:42Z | - |
dc.date.issued | 2019-04 | - |
dc.identifier.citation | ANALYTICAL CHEMISTRY, v. 91, NO 7, Page. 4868-4875 | en_US |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.issn | 1520-6882 | - |
dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acs.analchem.9b00624 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/111685 | - |
dc.description.abstract | The viscosity of biofluids can be used to acquire meaningful medical information on the conditions of a patient but has seldom been utilized in clinical practices owing to cumbersome measurement procedures and the need for large sample volumes. We present a colorimetric method to measure the viscosity of blood plasma using a paper-based viscometer developed in this study specifically for clinical diagnosis. The proposed analytical device consists of multilayered papers with fluid-loading, -mixing, and -measuring regions, and it can be fabricated readily in a simple manner using three-layered paper channels and tape. Moreover, the colorimetric analysis enables viscosity estimations by analyzing a single optical image. To validate the device performance, we measured the viscosities of fluids such as glycerin aqueous solutions, bovine-serum-albumin solution, dimethyl sulfoxide, and blood plasma. We found that the measured viscosities were in good agreement with the reference values. Finally, we developed a simple smartphone application for the viscosity measurements that helped enhance the convenience and utility of the paper-based viscometer while maintaining the measurement accuracy. | en_US |
dc.description.sponsorship | This work was financially supported by a National Research Foundation of Korea (NRF) grant funded by the Korea government (Nos. 2012R1A6A1029029, 2016R1A2B3009541, and 2018R1A6A3A11043917). | en_US |
dc.language.iso | en | en_US |
dc.publisher | AMER CHEMICAL SOC | en_US |
dc.subject | MICROFLUIDIC VISCOMETER | en_US |
dc.subject | ANALYTICAL DEVICE | en_US |
dc.subject | SURFACE-TENSION | en_US |
dc.subject | VISCOSITY | en_US |
dc.subject | FLOW | en_US |
dc.subject | POINT | en_US |
dc.subject | CONSTITUENTS | en_US |
dc.subject | DYNAMICS | en_US |
dc.subject | CHANNEL | en_US |
dc.subject | SERUM | en_US |
dc.title | Development of a Paper-Based Viscometer for Blood Plasma Using Colorimetric Analysis | en_US |
dc.type | Article | en_US |
dc.relation.no | 7 | - |
dc.relation.volume | 91 | - |
dc.identifier.doi | 10.1021/acs.analchem.9b00624 | - |
dc.relation.page | 4868-4875 | - |
dc.relation.journal | ANALYTICAL CHEMISTRY | - |
dc.contributor.googleauthor | Kang, Hyunwoong | - |
dc.contributor.googleauthor | Jang, Ilhoon | - |
dc.contributor.googleauthor | Song, Simon | - |
dc.contributor.googleauthor | Bae, Sang-Cheol | - |
dc.relation.code | 2019001589 | - |
dc.sector.campus | S | - |
dc.sector.daehak | RESEARCH INSTITUTE[S] | - |
dc.sector.department | INSTITUTE OF NANO SCIENCE AND TECHNOLOGY | - |
dc.identifier.pid | iroonjang | - |
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