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dc.contributor.author김진기-
dc.date.accessioned2019-09-04T06:17:30Z-
dc.date.available2019-09-04T06:17:30Z-
dc.date.issued2005-02-
dc.identifier.citationJOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, v. 28, No. 10, Page. 1593-1604en_US
dc.identifier.issn1082-6076-
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1081/JLC-200058377-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/110200-
dc.description.abstractA reproducible and specific high performance liquid chromatography (HPLC) method was developed to quantity plasma levels of acemetacin and its metabolite, indometacin in order to conduct a pharmacokinetics study. Plasma samples were prepared by liquid-liquid extraction using ethyl acetate.- Extracted samples were analyzed on a reverse-phase C-18 column with a mobile phase consisting of 20mM phosphate buffer (pH 2.9) and acetonitrile (60:40, v/v) and UV detection at 254nm. Using this method, the phannacokinctics study was carried out on eight volunteers after a single oral administration.en_US
dc.description.sponsorshipThis work was supported by the Korea Food and Drug Administration Grant (KFDA‐02142‐EQI‐533).en_US
dc.language.isoen_USen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.subjectacemetacinen_US
dc.subjectindometacinen_US
dc.subjecthigh performance liquid chromatography (HPLC)en_US
dc.titleHPLC method for the pharmacokinetics study of acemetacin in human plasmaen_US
dc.typeArticleen_US
dc.relation.no10-
dc.relation.volume28-
dc.identifier.doi10.1081/JLC-200058377-
dc.relation.page1593-1604-
dc.relation.journalJOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES-
dc.contributor.googleauthorBan, Eunmi-
dc.contributor.googleauthorCho, Jung‐Hye-
dc.contributor.googleauthorJang, Dong‐Jin-
dc.contributor.googleauthorPiao, Xiang‐Lan-
dc.contributor.googleauthorKim, Jin‐Ki-
dc.contributor.googleauthorJi, Jun‐Pil-
dc.contributor.googleauthorKim, Chong‐Kook-
dc.relation.code2007205340-
dc.sector.campusE-
dc.sector.daehakCOLLEGE OF PHARMACY[E]-
dc.sector.departmentDEPARTMENT OF PHARMACY-
dc.identifier.pidjinkikim-
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COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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