Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진기 | - |
dc.date.accessioned | 2019-09-04T06:17:30Z | - |
dc.date.available | 2019-09-04T06:17:30Z | - |
dc.date.issued | 2005-02 | - |
dc.identifier.citation | JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, v. 28, No. 10, Page. 1593-1604 | en_US |
dc.identifier.issn | 1082-6076 | - |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1081/JLC-200058377 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/110200 | - |
dc.description.abstract | A reproducible and specific high performance liquid chromatography (HPLC) method was developed to quantity plasma levels of acemetacin and its metabolite, indometacin in order to conduct a pharmacokinetics study. Plasma samples were prepared by liquid-liquid extraction using ethyl acetate.- Extracted samples were analyzed on a reverse-phase C-18 column with a mobile phase consisting of 20mM phosphate buffer (pH 2.9) and acetonitrile (60:40, v/v) and UV detection at 254nm. Using this method, the phannacokinctics study was carried out on eight volunteers after a single oral administration. | en_US |
dc.description.sponsorship | This work was supported by the Korea Food and Drug Administration Grant (KFDA‐02142‐EQI‐533). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | TAYLOR & FRANCIS INC | en_US |
dc.subject | acemetacin | en_US |
dc.subject | indometacin | en_US |
dc.subject | high performance liquid chromatography (HPLC) | en_US |
dc.title | HPLC method for the pharmacokinetics study of acemetacin in human plasma | en_US |
dc.type | Article | en_US |
dc.relation.no | 10 | - |
dc.relation.volume | 28 | - |
dc.identifier.doi | 10.1081/JLC-200058377 | - |
dc.relation.page | 1593-1604 | - |
dc.relation.journal | JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | - |
dc.contributor.googleauthor | Ban, Eunmi | - |
dc.contributor.googleauthor | Cho, Jung‐Hye | - |
dc.contributor.googleauthor | Jang, Dong‐Jin | - |
dc.contributor.googleauthor | Piao, Xiang‐Lan | - |
dc.contributor.googleauthor | Kim, Jin‐Ki | - |
dc.contributor.googleauthor | Ji, Jun‐Pil | - |
dc.contributor.googleauthor | Kim, Chong‐Kook | - |
dc.relation.code | 2007205340 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF PHARMACY[E] | - |
dc.sector.department | DEPARTMENT OF PHARMACY | - |
dc.identifier.pid | jinkikim | - |
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