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Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting

Title
Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting
Author
김종호
Issue Date
2006-10
Publisher
AMER CHEMICAL SOC
Citation
ANALYTICAL CHEMISTRY, v. 78, No. 19, Page. 6967-6973
Abstract
We have developed biocompatible, photostable, and multiplexing-compatible surface-enhanced Raman spectroscopic tagging material (SERS dots) composed of silver nanoparticle-embedded silica spheres and organic Raman labels for cellular cancer targeting in living cells. SERS dots showed linear dependency of Raman signatures on their different amounts, allowing their possibility for the quantification of targets. In addition, the antibody-conjugated SERS dots were successfully applied to the targeting of HER2 and CD10 on cellular membranes and exhibited good specificity. SERS dots demonstrate the potential for high-throughput screening of biomolecules using vibrational information.
URI
https://pubs.acs.org/doi/abs/10.1021/ac0607663https://repository.hanyang.ac.kr/handle/20.500.11754/108753
ISSN
0003-2700
DOI
10.1021/ac0607663
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > MATERIALS SCIENCE AND CHEMICAL ENGINEERING(재료화학공학과) > Articles
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