The cytotoxic saponin from heat-processed Achyranthes fauriei roots
- Title
- The cytotoxic saponin from heat-processed Achyranthes fauriei roots
- Author
- 유혜현
- Keywords
- Achyranthes fauriei; Amaranthaceae; cytotoxic activity; bioassay-linked HPLC-ELSD; chikusetsusaponin IVa
- Issue Date
- 2006-05
- Publisher
- PHARMACEUTICAL SOC JAPAN
- Citation
- BIOLOGICAL & PHARMACEUTICAL BULLETIN, v. 29, No. 5, Page. 1053-1055
- Abstract
- An extract of heat-processed Achyranthes fauriei roots showed more potent cytotoxic activity against human hepatoma SK-Hep-1 cells than that of the crude plant. Employing a bioassay-linked HPLC-ELSD (high performance liquid chromatography-evaporative light scattering detector) method, followed by silica gel column chromatography, a cytotoxic triterpenoid saponin, chikusetsusaponin IVa was isolated. It is contributive to the increased cytotoxic activity of the heat-processed. The amount of chikusetsusaponin IVa from the roots of Achyranthes fauriei was significantly increased after heat-processing.
- URI
- https://www.jstage.jst.go.jp/article/bpb/29/5/29_5_1053/_article/-char/ja/https://repository.hanyang.ac.kr/handle/20.500.11754/107980
- ISSN
- 0918-6158
- DOI
- 10.1248/bpb.29.1053
- Appears in Collections:
- COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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