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Comparison of Seropositivity to Trichomonas vaginalis between Men with Prostatic Tumor and Normal Men

Title
Comparison of Seropositivity to Trichomonas vaginalis between Men with Prostatic Tumor and Normal Men
Author
황환식
Keywords
Trichomonas vaginalis; seropositivity; benign prostate hyperplasia; prostate cancer
Issue Date
2019-02
Publisher
대한기생충학회
Citation
THE KOREAN JOURNAL OF PARASITOLOGY, v. 57, NO 1, Page. 21-25
Abstract
Trichomoniasis is the most common curable sexually-transmitted infection. Most Trichomonas vaginalis-infect- ed men are asymptomatic and can remain undiagnosed and untreated, and this has been thought to result in chronic persistent prostatic infection. Chronic inflammation is regarded as the major factor in the pathogenesis and progression of benign prostatic hyperplasia (BPH) and prostatic cancer (PCa). The aim of this study is to identify seropositivity to T. vaginalis in men with prostate tumors (BPH or PCa) visited to Hanyang University Hospital. A total of 183 men were en- rolled between October 2013 and November 2014. They consisted of 139 with BPH (mean age: 64.0 ± 0.07) and 44 with prostate cancer (mean age: 73.3±0.18). We carried out ELISA to identify the seropositivity to T. vaginalis. Mixed lysate antigen extracted from 8 strains of T. vaginalis was used in the ELISA. Also 58 male outpatients visited to Health Promo- tion Center in Hanyang University Hospital were evaluated for comparing group. As a results, seropositivity to T. vaginalis in patients with prostatic diseases was 19.7% (BPH: 18.7%, PCa: 22.7%) and it was significantly higher than the 1.7% of the comparing healthy group (P = 0.001). Therefore, prostatic tumor showed higher seropositivity against T. vaginalis than normal men. As far as we know, this is the first report about seroprevalence in prostatic tumor in Korea.
URI
http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2019.57.1.21https://repository.hanyang.ac.kr/handle/20.500.11754/107433
ISSN
0023-4001; 1738-0006
DOI
10.3347/kjp.2019.57.1.21
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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