146 47

Full metadata record

DC FieldValueLanguage
dc.contributor.author윤영은-
dc.date.accessioned2019-05-28T01:12:23Z-
dc.date.available2019-05-28T01:12:23Z-
dc.date.issued2017-01-
dc.identifier.citationYONSEI MEDICAL JOURNAL, v. 58, no. 2, page. 388-394en_US
dc.identifier.issn0513-5796-
dc.identifier.issn1976-2437-
dc.identifier.urihttps://synapse.koreamed.org/DOIx.php?id=10.3349/ymj.2017.58.2.388-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/106055-
dc.description.abstractPurpose: Distinguishing infiltrative renal cell carcinoma (RCC) from transitional cell carcinoma (TCC) is a challenging issue due to their radiologic similarities. We evaluated systemic inflammatory biomarkers as parameters for distinguishing tumor types.Materials and Methods: A computerized search of medical records from November 2005 to October 2015 identified 116 patients with infiltrative renal masses who were difficult to diagnose confirmatively in radiological study. We investigated the diagnostic efficacy among these patients with their preoperative absolute neutrophil counts (ANC), absolute lymphocyte counts (ALC), absolute monocyte counts (AMC), neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR).Results: The infiltrative RCC group demonstrated significantly lower ALC {1449/mu L (1140-1896), median [interquartile range (IQR)]} than the TCC group [1860/mu L (1433-2342), p=0.016]. LMR [median (IQR)] also was lower in the infiltrative RCC group [2.98 (2.32-4.14) vs. TCC group 4.10 (2.86-6.09); p=0.011]. In subgroup analysis, non-metastatic infiltrative RCC showed lower ALC and LMR and higher NLR than non-metastatic TCC. Within non-metastatic infiltrative renal masses, multivariate logistic regression analysis revealed that younger patient age and lower LMR were associated with infiltrative RCC [odds ratios (OR) 0.874, p=0.024 and OR 0.461, p=0.048, respectively]. Receiver operating characteristic curve analysis showed that younger age and lower LMR were highly predictive of non-metastatic RCC (area under the curve=0.919, p<0.001).Conclusion: Age and LMR were significantly different between patients with infiltrative renal mass. These are potential markers for distinguishing between infiltrative RCC and TCC without metastasis.en_US
dc.language.isoenen_US
dc.publisherYONSEI UNIV COLL MEDICINEen_US
dc.subjectInfiltrationen_US
dc.subjectrenal cell carcinomaen_US
dc.subjecttransitional cell carcinomaen_US
dc.subjectlymphocyteen_US
dc.subjectmonocyteen_US
dc.titlePreoperative Lymphocyte-Monocyte Ratio Ameliorates the Accuracy of Differential Diagnosis in Non-Metastatic Infiltrative Renal Massesen_US
dc.typeArticleen_US
dc.identifier.doi10.3349/ymj.2017.58.2.388-
dc.relation.journalYONSEI MEDICAL JOURNAL-
dc.contributor.googleauthorHan, Jang Hee-
dc.contributor.googleauthorYoon, Young Eun-
dc.contributor.googleauthorKim, Sook Young-
dc.contributor.googleauthorCho, Young In-
dc.contributor.googleauthorRha, Koon Ho-
dc.contributor.googleauthorChoi, Young Deuk-
dc.contributor.googleauthorHan, Woong Kyu-
dc.relation.code2017000525-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidurologistyoon-


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE