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Graphene oxide-encoded Ag nanoshells with single-particle detection sensitivity towards cancer cell imaging based on SERRS

Title
Graphene oxide-encoded Ag nanoshells with single-particle detection sensitivity towards cancer cell imaging based on SERRS
Author
김종호
Keywords
ENHANCED RAMAN-SCATTERING; NANOPARTICLE PROBES; SILVER NANOSHELLS; MOLECULE
Issue Date
2015-03
Publisher
ROYAL SOC CHEMISTRY
Citation
ANALYST, v. 140, No. 10, Page. 3362-3367
Abstract
Developing ultrasensitive Raman nanoprobes is one of the emerging interests in the field of biosensing and bioimaging. Herein, we constructed a new type of surface-enhanced resonance Raman scattering nanoprobe composed of an Ag nanoshell as a surface-enhanced Raman scattering-active nanostructure, which was encapsulated with 4,7,10-trioxa-1,13-tridecanediamine-functionalized graphene oxide as an ultrasensitive Raman reporter exhibiting strong resonance Raman scattering including distinct D and G modes. The designed nanoprobe was able to produce much more intense and simpler Raman signals even at a single particle level than the Ag nanoshell bearing a well-known Raman reporter, which is beneficial for the sensitive detection of a target in a complex biological system. Finally, this ultrasensitive nanoprobe successfully demonstrated its potential for bioimaging of cancer cells using Raman spectroscopy.
URI
https://pubs.rsc.org/en/content/articlehtml/2015/an/c4an02382jhttps://repository.hanyang.ac.kr/handle/20.500.11754/106006
ISSN
0003-2654; 1364-5528
DOI
10.1039/c4an02382j
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > MATERIALS SCIENCE AND CHEMICAL ENGINEERING(재료화학공학과) > Articles
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