Sequence Variations in the Non-Coding Sequence of CTX Phages in Vibrio cholerae
- Title
- Sequence Variations in the Non-Coding Sequence of CTX Phages in Vibrio cholerae
- Author
- 김은진
- Keywords
- V. cholerae; CTX phage; non-coding sequence
- Issue Date
- 2016-08
- Publisher
- KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY
- Citation
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v. 26, No. 8, Page. 1473-1480
- Abstract
- This study focused on the variations in the non-coding sequences between ctxB and rstR of various CTX phages. The non-coding sequences of CTX-1 and CTX-cla are phage type-specific. The length of the non-coding region of CTX-1 and CTX-cla is 601 and 730 nucleotides, respectively. The non-coding sequence of CTX phage could be divided into three regions. There is a phage type-specific Variable region between two homologous Common regions (Common regions 1 and 2). The non-coding sequence of RS1 element is similar to CTX-1 except that Common region 1 is replaced by a short RS1-specific sequence. The non-coding sequences of CTX-2 and CTX-cla are homologous, indicating the non-coding sequence of CTX-2 is derived from CTX-cla. The non-coding region of CTX-O139 is similar to CTX-cla and CTX-2; however, it contains an extra phage type-specific sequence between Common region 2 and rstR. The variations in the non-coding sequences of CTX phages might be associated with the difference in the replication efficiency and the directionality in the integration into the V. cholerae chromosome.
- URI
- http://www.jmb.or.kr/journal/view.html?doi=10.4014/jmb.1604.04022https://repository.hanyang.ac.kr/handle/20.500.11754/105898
- ISSN
- 1017-7825; 1738-8872
- DOI
- 10.4014/jmb.1604.04022
- Appears in Collections:
- ETC[S] > 연구정보
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