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Rabies Virus-Inspired Silica-Coated Gold Nanorods as a Photothermal Therapeutic Platform for Treating Brain Tumors

Title
Rabies Virus-Inspired Silica-Coated Gold Nanorods as a Photothermal Therapeutic Platform for Treating Brain Tumors
Author
최한곤
Keywords
DRUG-DELIVERY; CELLULAR UPTAKE; GENE DELIVERY; NANOPARTICLES; SHAPE; CELLS; SIZE; MECHANISMS; PARTICLES; CONJUGATE
Issue Date
2017-05
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED MATERIALS, v. 29, No. 13, Article no. 1605563
Abstract
Rabies virus-inspired silica-coated gold nanorods are fabricated by mimicking size, shape, surface glycoprotein property and in vivo behavior of the rabies virus. These nanorods not only resemble the appearance of the actual rabies virus but also travel into the brain through the neuronal pathway bypassing the bloodbrain barrier, and moreover respond to near-infrared laser (808 nm) irradiation, emit heat, and effectively suppress brain tumors.
URI
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201605563https://repository.hanyang.ac.kr/handle/20.500.11754/103275
ISSN
0935-9648; 1521-4095
DOI
10.1002/adma.201605563
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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