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How many times should we repeat measuring liver stiffness using shear wave elastography?: 5-repetition versus 10-repetition protocols.

Title
How many times should we repeat measuring liver stiffness using shear wave elastography?: 5-repetition versus 10-repetition protocols.
Author
손주현
Keywords
Diffuse liver disease; Shear wave elastography; Liver stiffness measurement; Intra-observer variation
Issue Date
2016-12
Publisher
ELSEVIER SCIENCE BV
Citation
ULTRASONICS, v. 72, Page. 158-164
Abstract
The purpose of this study is to evaluate whether a 5-repetition liver stiffness (LS) measurement as the standard protocol of shear wave elastography (SWE) is comparable to a conventional 10-repetition measurement protocol and to identify factors that influence the reliability of the 5-repetition protocol. A total of 346 patients (mean, 48.0 years; range, 15-81 years, M:F = 192:154) who underwent SWE were enrolled. The median, first quartile, third quartile, and interquartile range divided by the median (IQR/M) of LS measurement were calculated and compared between 5-repetition and 10-repetition protocols. Subgroup analyses were also performed to identify factors associated with measurement reliability. The overall mean LS from the 10-repetition protocol was 7.97 kPa, which was not significantly different from the mean LS of the 5-repetition protocol (7.91 kPa; p = 0.192). However, the third quartile and IQR/M values of the two groups were significantly different from each other (p = 0.003 and <0.001). Subgroup analysis revealed that the 5-repetition results were significantly different from the 10-repetition results in the fatty liver and high LS subgroups. Therefore, the 5-repetition SWE measurement protocol can replace the conventional 10-repetition protocol, with the exception of patients with fatty liver disease or an LS value higher than 10 kPa. (C) 2016 Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S0041624X1630138X?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/102357
ISSN
0041-624X; 1874-9968
DOI
10.1016/j.ultras.2016.08.005
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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