Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박용천 | - |
dc.date.accessioned | 2019-04-18T06:16:06Z | - |
dc.date.available | 2019-04-18T06:16:06Z | - |
dc.date.issued | 2016-12 | - |
dc.identifier.citation | ACTA NEUROPSYCHIATRICA, V. 28, NO 6, Page. 337-345 | en_US |
dc.identifier.issn | 1601-5215 | - |
dc.identifier.uri | https://www.cambridge.org/core/journals/acta-neuropsychiatrica/article/suicidal-thoughtsacts-and-clinical-correlates-in-patients-with-depressive-disorders-in-asians-results-from-the-reapad-study/4860D3599EEFAD4AA005956F46CA1843 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/102331 | - |
dc.description.abstract | Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) study, we aimed to present the rates and clinical correlates of suicidal thoughts/acts in patients recruited from a total of 40 centres in 10 Asian countries/areas: China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand. Methods: Data from 1122 patients with depressive disorders in the REAP-AD study were used. The ICD-10 was employed to diagnose depressive episodes and recurrent depressive disorder. The presence or absence of suicidal thoughts/acts and profile of other depressive symptoms was established using the National Institute for Health and Clinical Excellence guidelines for depression. Country/area differences in rates of suicidal thoughts/acts were evaluated with the chi(2) test. In addition, depressive symptom profiles, other clinical characteristics, and patterns of psychotropic drug prescription in depressed patients with and without suicidal thoughts/acts were compared using analysis of covariance for continuous variables and logistic regression analysis for discrete variables to adjust the effects of covariates. Results: The rates of suicidal thoughts/acts in 10 countries/areas varied from 12.8% in Japan to 36.3% in China. Patients with suicidal thoughts/acts presented more persistent sadness (adjusted odds ratio [aOR] = 2.64, p˂0.001), loss of interest (aOR = 2.33, p˂0.001), fatigue (aOR = 1.58, p˂0.001), insomnia (aOR = 1.74, p˂0.001), poor concentration (aOR = 1.88, p˂0.001), low self-confidence (aOR = 1.78, p˂0.001), poor appetite (aOR = 2.27, p˂0.001), guilt/self-blame (aOR = 3.03, p˂0.001), and use of mood stabilisers (aOR = 1.79, p˂0.001) than those without suicidal thoughts/acts. Conclusion: Suicidal thoughts/acts can indicate greater severity of depression, and are associated with a poorer response to antidepressants and increased burden of illness. Hence, suicidal thoughts/acts can provide a clinical index reflecting the clinical status of depressive disorders in Asians. | en_US |
dc.language.iso | en | en_US |
dc.publisher | CAMBRIDGE UNIV PRESS | en_US |
dc.subject | Asians | en_US |
dc.subject | depressive disorders | en_US |
dc.subject | mood stabilisers | en_US |
dc.subject | suicidal thoughts/acts | en_US |
dc.title | Suicidal thoughts/acts and clinical correlates in patients with depressive disorders in Asians: results from the REAP-AD study | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 28 | - |
dc.identifier.doi | 10.1017/neu.2016.27 | - |
dc.relation.page | 337-345 | - |
dc.relation.journal | ACTA NEUROPSYCHIATRICA | - |
dc.contributor.googleauthor | Park, Seon-Cheol | - |
dc.contributor.googleauthor | Lee, Min-Soo | - |
dc.contributor.googleauthor | Hahn, Sang Woo | - |
dc.contributor.googleauthor | Si, Tian-Mei | - |
dc.contributor.googleauthor | Kanba, Shigenobu | - |
dc.contributor.googleauthor | Chong, Mian-Yoon | - |
dc.contributor.googleauthor | Yoon, Chee Kok | - |
dc.contributor.googleauthor | Udomratn, Pichet | - |
dc.contributor.googleauthor | Tripathi, Adarsh | - |
dc.contributor.googleauthor | Park, Yong Chon | - |
dc.relation.code | 2016009561 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hypyc | - |
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