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dc.contributor.author송충길-
dc.date.accessioned2019-04-11T01:06:14Z-
dc.date.available2019-04-11T01:06:14Z-
dc.date.issued2016-12-
dc.identifier.citationBIOSENSORS & BIOELECTRONICS, v. 86, Page. 548-556en_US
dc.identifier.issn0956-5663-
dc.identifier.issn1873-4235-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0956566316306819?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/101684-
dc.description.abstractA label-free immunosensor based on electrochemical impedance spectroscopy has been developed for the sensitive detection of a cardiac biomarker myoglobin (cMyo). Hydrothermally synthesized graphene quantum dots (GQDs) have been used as an immobilized template on screen printed electrodes for the construction of an impedimetric sensor platform. The GQDs-modified electrode was conjugated with highly specific anti-myoglobin antibodies to develop the desired immunosensor. The values of charge transfer resistance (R-ct) were monitored as a function of varying antigen concentration. The R-ct value of the immunosensor showed a linear increase (from 0.20 to 0.31 k Omega) in the range of 0.01-100 ng/mL cMyo. The specific detection of cMyo was also made in the presence of other competing proteins. The limit of detection for the proposed immunosensor was, estimated as 0.01 ng/mL which is comparable to the standard ELISA techniques. (C) 2016 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipThe present research work has been funded through CSIR, India grant (OMEGA/PSC0202/2.2.5) from CSIR, India. Satish Kumar Tuteja also thanks the CSIR, India his senior research fellowship. We are grateful to the Director, CSIR-CSIO, Chandigarh, India.en_US
dc.language.isoenen_US
dc.publisherELSEVIER ADVANCED TECHNOLOGYen_US
dc.subjectGraphene quantum dotsen_US
dc.subjectMyoglobinen_US
dc.subjectElectrochemical Impedance Spectroscopyen_US
dc.subjectLabel-free immunosensoren_US
dc.subjectCardiac markeren_US
dc.titleA label-free electrochemical immunosensor for the detection of cardiac marker using graphene quantum dots (GQDs)en_US
dc.typeArticleen_US
dc.relation.volume86-
dc.identifier.doi10.1016/j.bios.2016.07.052-
dc.relation.page548-556-
dc.relation.journalBIOSENSORS & BIOELECTRONICS-
dc.contributor.googleauthorTuteja, Satish K.-
dc.contributor.googleauthorChen, Rui-
dc.contributor.googleauthorKukkar, Manil-
dc.contributor.googleauthorSong, Chung Kil-
dc.contributor.googleauthorMutreja, Ruchi-
dc.contributor.googleauthorSingh, Suman-
dc.contributor.googleauthorPaul, Ashok K.-
dc.contributor.googleauthorLee, Haiwon-
dc.contributor.googleauthorKim, Ki-Hyun-
dc.contributor.googleauthorDeep, Akash-
dc.relation.code2016001453-
dc.sector.campusS-
dc.sector.daehakRESEARCH INSTITUTE[S]-
dc.sector.departmentINSTITUTE OF NANO SCIENCE AND TECHNOLOGY-
dc.identifier.pidsaintck-
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