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Predictive factors for recurrence and clinical outcomes in patients with chronic subdural hematoma

Title
Predictive factors for recurrence and clinical outcomes in patients with chronic subdural hematoma
Author
한명훈
Keywords
body mass index; chronic subdural hematoma; recurrence; modified Rankin Scale; trauma; vascular disorders
Issue Date
2016-12
Publisher
AMER ASSOC NEUROLOGICAL SURGEONS
Citation
JOURNAL OF NEUROSURGERY, v.127, Issue 5, Page. 1117-1125
Abstract
OBJECTIVE Chronic subdural hematoma (CSDH) is a common type of intracranial hemorrhage in elderly patients. Many studies have suggested various factors that may be associated with the recurrence of CSDH. However, the results are inconsistent. The purpose of this study was to determine the associations among patient factors, recurrence, and clinical outcomes of CSDH after bur hole surgery performed during an 11-year period at twin hospitals. METHODS Kaplan-Meier analysis was performed to evaluate the risk factors for CSDH recurrence. Univariate and multivariate Cox proportional hazards regression analyses were used to calculate hazard ratios with 95% CIs for CSDH recurrence based on many variables. One-way repeated-measures ANOVA was used to assess the differences in the mean modified Rankin Scale score between categories for each risk factor during each admission and at the last follow-up. RESULTS This study was a retrospective analysis of 756 consecutive patients with CSDH who underwent bur hole surgery at the Hanyang University Medical Center (Seoul and Guri) between January 1, 2004, and December 31, 2014. During the 6-month follow-up, 104 patients (13.8%) with recurrence after surgery for CSDH were identified. Independent risk factors for recurrence were as follows: age > 75 years (HR 1.72, 95% CI 1.03–2.88; p = 0.039), obesity (body mass index ≥ 25.0 kg/m2), and a bilateral operation. CONCLUSIONS This study determined the risk factors for recurrence of CSDH and their effects on outcomes. Further studies are needed to account for these observations and to determine their underlying mechanisms.
URI
https://thejns.org/view/journals/j-neurosurg/127/5/article-p1117.xmlhttps://repository.hanyang.ac.kr/handle/20.500.11754/101647
ISSN
0022-3085; 1933-0693
DOI
10.3171/2016.8.JNS16867
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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