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Influence of Parent Artery Segmentation and Boundary Conditions on Hemodynamic Characteristics of Intracranial Aneurysms

Title
Influence of Parent Artery Segmentation and Boundary Conditions on Hemodynamic Characteristics of Intracranial Aneurysms
Author
오제훈
Keywords
Intracranial aneurysms; hemodynamic factors; parent artery segmentation; boundary conditions; computational fluid dynamics; COMPUTATIONAL FLUID-DYNAMICS; WALL SHEAR-STRESS; CEREBRAL ANEURYSMS; FLOW DYNAMICS; RISK-FACTORS; BLOOD-FLOW; RUPTURE; MODEL; SENSITIVITY; SIMULATION
Issue Date
2015-09
Publisher
YONSEI UNIV COLL MEDICINE
Citation
YONSEI MEDICAL JOURNAL, v. 56, No. 5, Page. 1328-1337
Abstract
Purpose: The purpose of this study is to explore the influence of segmentation of the upstream and downstream parent artery and hemodynamic boundary conditions (BCs) on the evaluated hemodynamic factors for the computational fluid dynamics (CFD) analysis of intracranial aneurysms. Materials and Methods: Three dimensional-patient-specific aneurysm models were analyzed by applying various combinations of inlet and outlet BCs. Hemodynamic factors such as velocity pattern, streamline, wall shear stress, and oscillatory shear index at the systolic time were visualized and compared among the different cases. Results: Hemodynamic factors were significantly affected by the inlet BCs while there was little influence of the outlet BCs. When the inlet length was relatively short, different inlet BCs showed different hemodynamic factors and the calculated hemodynamic factors were also dependent on the inlet length. However, when the inlet length (L) was long enough (L˃20D, where D is the diameter of inlet section), the hemodynamic factors became similar regardless of the inlet BCs and lengths. The error due to different inlet BCs was negligible. The effect of the outlet length on the hemodynamic factors was similar to that of the inlet length. Conclusion: Simulated hemodynamic factors are highly sensitive to inlet BCs and upstream parent artery segmentation. The results of this work can provide an insight into how to build models and to apply BCs for more accurate estimation of hemodynamic factors from CFD simulations of intracranial aneurysms.
URI
https://synapse.koreamed.org/DOIx.php?id=10.3349/ymj.2015.56.5.1328https://repository.hanyang.ac.kr/handle/20.500.11754/101532
ISSN
0513-5796; 1976-2437
DOI
10.3349/ymj.2015.56.5.1328
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > MECHANICAL ENGINEERING(기계공학과) > Articles
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