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dc.contributor.author정민성-
dc.date.accessioned2019-03-26T01:03:37Z-
dc.date.available2019-03-26T01:03:37Z-
dc.date.issued2016-11-
dc.identifier.citationEUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, v. 35, Issue 11,Page. 1771-1776en_US
dc.identifier.issn0934-9723-
dc.identifier.issn1435-4373-
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs10096-016-2725-6-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/101188-
dc.description.abstractPurpose The purpose of this study was to investigate the impact of malignancy and chemotherapy on the clinical and microbiological characteristics of Clostridium difficile infections (CDI). Methods CDI patients with a history of malignancy within 5 years were defined as the cancer group. The characteristics of the patients were compared according to the presence of malignancy. Results Of 580 patients with CDI, 159 (27.4 %) belonged to the cancer group and 421 (72.6 %) to the non-cancer group. More of the patients in the cancer group than those in the non-cancer group had been hospitalized within the prior 2 months (P < 0.001). Leukocytosis was more common in the non-cancer group (P = 0.034), while infection by PCR ribotype 017 strains was more common in the cancer group, with marginal significance (P = 0.07). Recurrence was more frequent in the cancer group (20.4 % vs. 9.5 %, P =0.005) and cancer was an independent risk factor for recurrence of CDI (OR = 2.66, 95 % CI 1.34-5.29, P =0.005). Age also contributed to the recurrence of CDI (OR = 1.03, 95 % CI 1.00-1.06, P =0.026). Conclusions Malignancy and age are independent risk factors for recurrence of CDI. Cancer patients require careful observation for recurrence after treatment of CDI.en_US
dc.description.sponsorshipThis work was supported by the research fund of Hanyang University (HY-2011).en_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.subjectADULT ONCOLOGY PATIENTSen_US
dc.subjectRISK-FACTORSen_US
dc.subjectHEALTH-CAREen_US
dc.subjectCLINICAL CHARACTERISTICSen_US
dc.subjectCANCER-PATIENTSen_US
dc.subjectEPIDEMIOLOGYen_US
dc.subjectDIARRHEAen_US
dc.subjectDISEASEen_US
dc.subjectCHEMOTHERAPYen_US
dc.subjectBI/NAP1/027en_US
dc.titleImpact of malignancy on Clostridium difficile infectionen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s10096-016-2725-6-
dc.relation.journalEUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES-
dc.contributor.googleauthorChung, M. S.-
dc.contributor.googleauthorKim, J.-
dc.contributor.googleauthorKang, J. O.-
dc.contributor.googleauthorPai, H.-
dc.relation.code2016001618-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidbovie-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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