Prognostic role of the Bethesda System for conventional papillary thyroid carcinoma
- Title
- Prognostic role of the Bethesda System for conventional papillary thyroid carcinoma
- Author
- 구혜령
- Keywords
- thyroid; papillary thyroid carcinoma; Bethesda System for Reporting Thyroid Cytopathology; fine-needle aspiration biopsy; prognosis
- Issue Date
- 2016-10
- Publisher
- WILEY-BLACKWELL
- Citation
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v. 38, NO. 10, Page. 1509-1514
- Abstract
- Background. The purpose of this study was to investigate the role of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) as a prognostic marker in conventional papillary thyroid carcinoma (PTC).
Methods. A total of 397 patients who underwent ultrasound-guided fine-needle aspiration biopsy (FNAB) and surgery for conventional PTCs were enrolled. The association between the Bethesda category and histopathologic result was evaluated.
Results. Among the Bethesda categories, a significant difference was found in the presence of extrathyroidal extension (Bethesda category III, 3.2% [7 of 220]; category V, 19.1% [42 of 220]; and category VI, 77.7% [171 of 220]; p <.001) and lymph node metastasis (Bethesda category III, 3.8% [6 of 156]; category V, 16.7% [26 of 156]; and category VI, 79.5% [124 of 156]; p <.001). Multivariate analysis showed that the Bethesda category was independently predictive of extrathyroidal extension (p =.013) and lymph node metastasis (p =.035).
Conclusion. Conventional PTC with a higher Bethesda category at the time of cytology diagnosis would be poor prognosis. (C) 2016 Wiley Periodicals, Inc.
- URI
- https://onlinelibrary.wiley.com/doi/full/10.1002/hed.24466https://repository.hanyang.ac.kr/handle/20.500.11754/100589
- ISSN
- 1043-3074; 1097-0347
- DOI
- 10.1002/hed.24466
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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