113 0

Full metadata record

DC FieldValueLanguage
dc.contributor.author이영복-
dc.date.accessioned2019-03-06T02:27:29Z-
dc.date.available2019-03-06T02:27:29Z-
dc.date.issued2016-10-
dc.identifier.citationCOLLOIDS AND SURFACES B-BIOINTERFACES, v. 146, Page. 544-549en_US
dc.identifier.issn0927-7765-
dc.identifier.issn1873-4367-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0927776516304829?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/100504-
dc.description.abstractThis study introduces a new type of uniform liposome-analogous vesicle with a highly stable shell structure in which water-in-oil-in-water double emulsion drops fabricated in a capillary-based microfluidic device are used as templates. The vesicles developed in this work consist of a poly(ethylene glycol) hydro gel core surrounded by a polyurethane (PU) film between 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) layers. Subjecting the double emulsion templates to UV irradiation leads to the formation of a PU elastomer film between the DPPC layers. The presence of a thin PU film sandwiched between the DPPC layers is confirmed by confocal laser microscopy. The thicknesses of the PU films are measured to be approximately similar to 4 mu m. Further study reveals the incorporation of the PU film between the DPPC layers remarkably improves the shell impermeability. Our vesicle system is expected to be useful for regulating the permeation of small molecules through lipid -based vesicular films. (C) 2016 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipThis work was supported by a grant of the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (Grant no.; A103017) and by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2008-0061891). M. Seo and A. Byun equally contributed to this work.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.subjectVesicleen_US
dc.subjectMicrofluidicsen_US
dc.subjectElastomer filmen_US
dc.subjectImpermeabilityen_US
dc.titleUniform and stable hydrogel-filled liposome-analogous vesicles with a thin elastomer shell layeren_US
dc.typeArticleen_US
dc.relation.volume146-
dc.identifier.doi10.1016/j.colsurfb.2016.06.052-
dc.relation.page544-549-
dc.relation.journalCOLLOIDS AND SURFACES B-BIOINTERFACES-
dc.contributor.googleauthorSeo, Mintae-
dc.contributor.googleauthorByun, Aram-
dc.contributor.googleauthorShim, Jongwon-
dc.contributor.googleauthorChoi, Hong Sung-
dc.contributor.googleauthorLee, Youngbok-
dc.contributor.googleauthorKim, Jin Woong-
dc.relation.code2016001589-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidyblee-
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE