Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이영복 | - |
dc.date.accessioned | 2019-03-06T02:27:29Z | - |
dc.date.available | 2019-03-06T02:27:29Z | - |
dc.date.issued | 2016-10 | - |
dc.identifier.citation | COLLOIDS AND SURFACES B-BIOINTERFACES, v. 146, Page. 544-549 | en_US |
dc.identifier.issn | 0927-7765 | - |
dc.identifier.issn | 1873-4367 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0927776516304829?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/100504 | - |
dc.description.abstract | This study introduces a new type of uniform liposome-analogous vesicle with a highly stable shell structure in which water-in-oil-in-water double emulsion drops fabricated in a capillary-based microfluidic device are used as templates. The vesicles developed in this work consist of a poly(ethylene glycol) hydro gel core surrounded by a polyurethane (PU) film between 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) layers. Subjecting the double emulsion templates to UV irradiation leads to the formation of a PU elastomer film between the DPPC layers. The presence of a thin PU film sandwiched between the DPPC layers is confirmed by confocal laser microscopy. The thicknesses of the PU films are measured to be approximately similar to 4 mu m. Further study reveals the incorporation of the PU film between the DPPC layers remarkably improves the shell impermeability. Our vesicle system is expected to be useful for regulating the permeation of small molecules through lipid -based vesicular films. (C) 2016 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | This work was supported by a grant of the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (Grant no.; A103017) and by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2008-0061891). M. Seo and A. Byun equally contributed to this work. | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCIENCE BV | en_US |
dc.subject | Vesicle | en_US |
dc.subject | Microfluidics | en_US |
dc.subject | Elastomer film | en_US |
dc.subject | Impermeability | en_US |
dc.title | Uniform and stable hydrogel-filled liposome-analogous vesicles with a thin elastomer shell layer | en_US |
dc.type | Article | en_US |
dc.relation.volume | 146 | - |
dc.identifier.doi | 10.1016/j.colsurfb.2016.06.052 | - |
dc.relation.page | 544-549 | - |
dc.relation.journal | COLLOIDS AND SURFACES B-BIOINTERFACES | - |
dc.contributor.googleauthor | Seo, Mintae | - |
dc.contributor.googleauthor | Byun, Aram | - |
dc.contributor.googleauthor | Shim, Jongwon | - |
dc.contributor.googleauthor | Choi, Hong Sung | - |
dc.contributor.googleauthor | Lee, Youngbok | - |
dc.contributor.googleauthor | Kim, Jin Woong | - |
dc.relation.code | 2016001589 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | yblee | - |
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