김철영
2019-05-22T01:02:44Z
2019-05-22T01:02:44Z
2018-01
CHEMISTRY & BIODIVERSITY, v. 15, No. 1, Article no. e1700447
1612-1872
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.201700447
https://repository.hanyang.ac.kr/handle/20.500.11754/105317
Four new (1 - 4) and one known (5) acylated iridoid glycosides were isolated from the aerial parts of Veronicastrum sibiricum (L.) Pennell. The chemical structures of the isolated compounds were determined to be 3,4-dicinnamoyl-6-O-rhamnopyranosyl-10-O-bergaptol-5,7-bisdeoxycynanchoside (1), 3,4-dicinnamoyl-6-O-rhamnopyranosylpaulownioside (2), 2,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (3), 3,4-dicinnamoyl-6-O-rhamnopyranosylaucubin (4), and 3,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (5) using spectroscopic techniques. Among these compounds, compound 5 increased antioxidant response element (ARE) luciferase activity.
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2016R1A2B4014598) and a grant from the Korean Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (HI14C0018).
en_US
WILEY-V C H VERLAG GMBH
Veronicastrum sibiricum (L; )
Pennell
Scrophulariaceae
acylated iridoid glycosides
antioxidant response element
ARE-luciferase reporter assay
Four New Acylated Iridoid Glycosides from the Aerial Part of Veronicastrum sibiricum and Their Antioxidant Response Element-Inducing Activity
Article
1
15
10.1002/cbdv.201700447
1-8
CHEMISTRY & BIODIVERSITY
Kim, Myeong Il
Kim, Chul Young
2018011683
E
COLLEGE OF PHARMACY[E]
DEPARTMENT OF PHARMACY
chulykim