신수진
2017-11-21T06:39:24Z
2017-11-21T06:39:24Z
2016-01
Journal of Pathology and Translational Medicine, v. 50, NO 1, Page. 26-36
2383-7837
2383-7845
http://jpatholtm.org/journal/view.php?doi=10.4132/jptm.2015.11.09
http://hdl.handle.net/20.500.11754/31737
Tubulointerstitial nephritis (TIN) is the most common form of renal involvement in IgG4-related disease. It is characterized by a dominant infiltrate of IgG4-positive plasma cells in the interstitium and storiform fibrosis. Demonstration of IgG4-positive plasma cells is essential for diagnosis, but the number of IgG4-positive cells and the ratio of IgG4-positive/IgG-positive plasma cells may vary from case to case and depending on the methods of tissue sampling even in the same case. IgG4-positive plasma cells can be seen in TIN associated with systemic lupus erythematosus, Sjögren syndrome, or anti-neutrophil cytoplasmic antibody-associated vasculitis, which further add diagnostic confusion and difficulties. To have a more clear view of IgG4-TIN and to delineate differential points from other TIN with IgG4-positive plasma cell infiltrates, clinical and histological features of IgG4-TIN and its mimickers were reviewed. In the rear part, cases suggesting overlap of IgG4-TIN and its mimickers and glomerulonephritis associated with IgG4-TIN were briefly described.
en
Korean Society of Pathologists
IgG4-related disease
Lupus nephritis
Sjogren's syndrome
Anti-neutrophil cytoplasmic antibody-associated vasculitis
Glomerulonephritis, membranous
Overview of IgG4-related tubulointerstitial nephritis and its mimickers
Article
1
50
10.4132/jptm.2015.11.09
26-36
Journal of Pathology and Translational Medicine
Jeong, Hyeon Joo
Shin, Su-Jin
Lim, Beom Jin
2016032826
S
COLLEGE OF MEDICINE[S]
DEPARTMENT OF MEDICINE
charm
http://orcid.org/0000-0001-9114-8438