이강홍
2017-04-18T00:36:10Z
2017-04-18T00:36:10Z
2015-08
JOURNAL OF GASTROINTESTINAL SURGERY, v. 19, NO 8, Page. 1513-1521
1091-255X
1873-4626
http://link.springer.com/article/10.1007/s11605-015-2834-z
http://hdl.handle.net/20.500.11754/26737
The relationship between visceral obesity and colon cancer outcome has not been well studied. The goal of this study was to determine the impact of visceral obesity on lymph node (LN) metastasis and overall survival (OS) in colon cancer. Metastatic LN ratio (MLR) was defined as the number of involved nodes by tumor divided by the total number of resected LNs. Visceral (VFA) and subcutaneous fat areas (SFA) were determined by measuring abdominal fat volume distribution via CT scan, and visceral obesity was defined as a VFA to total fat area ratio (V/T) ˃ 0.29. In a multivariate analysis among 186 patients, there were inverse associations between V/T and MLR (OR = 0.413, 95 % CI = 0.216-0.789, P = 0.007). Furthermore, patients with visceral obesity tended to have significantly better OS than patients with non-visceral obesity. Higher V/T ratios which indicate referring to visceral obesity was significantly associated with decreased MLR and better OS for CRC.
en
SPRINGER
Obesity
Visceral fat area
Lymph node
Metastasis
Colon cancer
Visceral Obesity Predicts Fewer Lymph Node Metastases and Better Overall Survival in Colon Cancer
Article
8
19
10.1007/s11605-015-2834-z
1513-1521
JOURNAL OF GASTROINTESTINAL SURGERY
Park, Se Woo
Lee, Hang Lak
Doo, Eun Young
Lee, Kang Nyeong
Jun, Dae Won
Lee, Oh Young
Han, Dong Soo
Yoon, Byung Chul
Choi, Ho Soon
Lee, Kang Hong
2015008913
S
COLLEGE OF MEDICINE[S]
DEPARTMENT OF MEDICINE
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