고성호
2016-08-05T05:45:42Z
2016-08-05T05:45:42Z
2015-02
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, v. 25, Page. 26-31
1059-1311
1532-2688
http://www.sciencedirect.com/science/article/pii/S1059131114003100
http://hdl.handle.net/20.500.11754/22454
Purpose: Depression is common in adults with epilepsy and an important factor that affects quality of life in these individuals. However, there are few studies on the interactions between epilepsy and family factors in adults and we here investigate this association. Methods: This cross-sectional, multicenter study collected data on 391 adults with epilepsy and their caregivers recruited from 27 hospitals throughout Korea. The Beck Depression Inventory (BDI), Stigma Scale, and Caregiver Burden Inventory (CBI) were used to evaluate the study population. Multivariate analysis was conducted using hierarchical linear regression. The Sobel test and structural equation modeling were used to examine interrelationships among the potential factors. Results: The mean patient BDI score was 16.3 (SD = 11.1). Depressive symptoms (BDI >= 10) were in 68.3% and 57.0% in patients and their caregivers, respectively. Hierarchical linear regression analysis only identified caregiver BDI (beta = 0.219; p < 0.001) as an independent factor related to patient BDI. The mediational model suggested that caregiver BDI mediated the effects of other family factors on patient BDI: caregiver's educational level (p = 0.002), caregiver's CBI score (p < 0.001), caregiver's Stigma Scale score (p < 0.001), and family APGAR score (p < 0.001). In addition, structural equation modeling showed that the relation between caregiver and patient BDI was unidirectional. Conclusion: Caregiver depression is the most important contributor to depression in adults with epilepsy. The other family factors such as caregiver's perception of burden and the level of family function are indirectly correlated with patient depression via the mediating effects of caregiver depression. (C) 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
Korea UCB Co., Limited
en
W B SAUNDERS CO LTD
Depression
Adult epilepsy
Caregiver
Family factors
Contribution of the family environment to depression in Korean adults with epilepsy
Article
25
10.1016/j.seizure.2014.11.011
26-31
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Han, Su-Hyun
Kim, Bomi
Lee, Sang-Ahm
the Korean QoL in Epilepsy Study Group
2015001120
S
COLLEGE OF MEDICINE[S]
DEPARTMENT OF MEDICINE
ksh213