한명훈
2019-12-08T14:52:19Z
2019-12-08T14:52:19Z
2018-07
SCIENTIFIC REPORTS, v. 8, Article no. 10178
2045-2322
https://www.nature.com/articles/s41598-018-28471-1
https://repository.hanyang.ac.kr/handle/20.500.11754/119421
Hydrocephalus is a common complication following subarachnoid haemorrhage (SAH) arising from spontaneous aneurysm rupture. The Hounsfield unit (HU) value from computed tomography scans may reflect bone mineral density, which correlates with body mass index, which in turn is related to postSAH ventricle size changes. We herein investigated potential associations between frontal skull HU values and ventricle size changes after SAH. HU values from four different areas in the frontal bone were averaged to minimize measurement errors. The bicaudate index and Evans ratio were measured using both baseline and follow-up CT images. CT images with bicaudate index >0.2 and Evans ratio > 0.3 simultaneously were defined as indicating ventriculomegaly. We included 232 consecutive patients with SAH due to primary spontaneous aneurysm rupture, who underwent clipping over almost a 9-year period at a single institution. The first tertile of frontal skull HU values in older patients (>= 55 years) was an independent predictor of ventriculomegaly after SAH, as compared to the third tertile in younger patients (hazard ratio, 4.01; 95% confidence interval 1.21-13.30; p = 0.023). The lower frontal skull HU value independently predicted ventricular enlargement post-SAH, due to the potential weak integrity of subarachnoid trabecular structures in younger patients.
en_US
NATURE PUBLISHING GROUP
BONE-MINERAL DENSITY
GLOBAL CEREBRAL ATROPHY
BODY-MASS INDEX
COLLAGEN TYPE-I
INTRACEREBRAL HEMORRHAGE
OSTEOGENESIS IMPERFECTA
COMPUTED-TOMOGRAPHY
HYDROCEPHALUS
CT
IMPACT
The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage
Article
8
10.1038/s41598-018-28471-1
0-0
SCIENTIFIC REPORTS
Won, Yu Deok
Na, Min Kyun
Kim, Choong Hyun
Kim, Jae Min
Cheong, Jin Hwan
Ryu, Je Il
Han, Myung-Hoon
2018003596
S
COLLEGE OF MEDICINE[S]
DEPARTMENT OF MEDICINE
gksmh80
http://orcid.org/0000-0003-1728-5017