3-D printable self-healing hydrogel for tissue engineering

Title
3-D printable self-healing hydrogel for tissue engineering
Other Titles
조직공학을 위한 3차원 프린팅이 가능한 자가치유 하이드로젤
Author
Roh, Hyun Ho
Alternative Author(s)
노현호
Advisor(s)
이근용
Issue Date
2019-02
Publisher
한양대학교
Degree
Master
Abstract
Three-dimensional (3-D) bioprinting has developed as an important method for tissue regeneration, with possibilities to construct functional and biological structures for various biomedical applications. Hydrogels were formed from oxidized hyaluronate (OHA) in the presence of glycol chitosan (GC) via Schiff base formation. Interestingly, autonomous healing of OHA/GC hydrogels after damage was achieved by incorporating adipic acid dihydrazide (ADH) into the gels. Also, alginate (ALG) was added to OHA/GC/ADH hydrogels to exploit dual cross-linking system, which remarkably enhanced structural stability of the gels without the loss of self-healing capability. Various characteristics of OHA/GC/ADH/ALG hydrogels including physiochemical properties, biocompatibility, and 3-D printability were investigated in vitro. In this thesis, self-healing behavior of OHA/GC/ADH/ALG hydrogels as well as their potential applications to 3-D bioprinting for cartilage tissue regeneration was investigated.
URI
http://dcollection.hanyang.ac.kr/common/orgView/000000109004http://repository.hanyang.ac.kr/handle/20.500.11754/99316
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIOENGINEERING(생명공학과) > Theses (Master)
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