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Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation

Title
Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation
Author
채필석
Keywords
FACIAL AMPHIPHILES; DETERGENT; CRYSTALLIZATION; TRANSPORT; RECEPTOR; CRYSTALLOGRAPHY; SOLUBILIZATION; SURFACTANTS; EXPRESSION; INSIGHTS
Issue Date
2016-10
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v. 52, NO. 81, Page. 12104-12107
Abstract
A novel class of detergents, designated tandem neopentyl glycol maltosides (TNMs), were evaluated with four target membrane proteins. The best detergent varied depending on the target, but TNM-C12L and TNM-C11S were notable for their ability to confer increased membrane protein stability compared to DDM. These agents have potential for use in membrane protein research.
URI
https://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC06147H#!divAbstracthttp://repository.hanyang.ac.kr/handle/20.500.11754/98952
ISSN
1359-7345; 1364-548X
DOI
10.1039/c6cc06147h
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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