55 0

Characteristics of a pandemic clone of O3: K6 and O4: K68 Vibrio parahaemolyticus isolated in Beira, Mozambique

Title
Characteristics of a pandemic clone of O3: K6 and O4: K68 Vibrio parahaemolyticus isolated in Beira, Mozambique
Author
김동욱
Keywords
FIELD GEL-ELECTROPHORESIS; STRAINS; O3-K6; EMERGENCE; DIARRHEA; SEROTYPE; SPREAD; MLST; multilocus sequence typing; ST; sequence type; UPGMA; unweighted-pair grouping with mathematical averaging; AP-PCR; arbitrarily primed PCR; GS-PCR; group-specific PCR
Issue Date
2008-12
Publisher
SOC GENERAL MICROBIOLOGY
Citation
JOURNAL OF MEDICAL MICROBIOLOGY, v. 57, No. 12, Page. 1502-1507
Abstract
The genetic characteristics of Vibrio parahaemolyticus strains isolated in 2004 and 2005 in Mozambique were assessed in this study to determine whether the pandemic clone of V. parahaemolyticus O3 : K6 and O4 : K68 serotypes has spread to Mozambique. Fifty-eight V. parahaemolyticus strains isolated from hospitalized diarrhoea patients in Beira, Mozambique, were serotyped for O : K antigens and genotyped for toxR, tdh and trh genes. A group-specific PCR, a PCR that detects the presence of ORF8 of the filamentous phage f237, arbitrarily primed PCR, PFGE and multilocus sequence typing were performed to determine the pandemic status of the strains and their ancestry. All strains of serovars O3 : K6 (n=38) and O4 : K68 (n=4) were identified as a pandemic clonal group by these analyses. These strains are closely related to the pandemic reference strains of O3 : K6 and O4 : K68, which emerged in Asia in 1996 and were later found globally. The pandemic serotypes O3 : K6 and O4 : K68 including reference strains grouped into a single cluster indicating emergence from a common ancestor. The O3 : K58 (n=8), O4 : K13 (n=6), O3 : KUT (n=1) and O8 : K41 (n=1) strains showed unique characteristics different from the pandemic clone.
URI
http://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.2008/004275-0http://repository.hanyang.ac.kr/handle/20.500.11754/80869
ISSN
0022-2615
DOI
10.1099/jmm.0.2008/004275-0
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE