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High efficiency production of astaxanthin by autotrophic cultivation of Haematococcus pluvialis in a bubble column photobioreactor

Title
High efficiency production of astaxanthin by autotrophic cultivation of Haematococcus pluvialis in a bubble column photobioreactor
Author
Katoh, Shigeo
Keywords
Haematococcus pluvialis; autotrophic culture; bubble column; fed-batch; nitrate concentration; astaxanthin
Issue Date
2008-05
Publisher
ELSEVIER SCIENCE SA
Citation
BIOCHEMICAL ENGINEERING JOURNAL, v. 39, No. 3, Page. 575-580
Abstract
Haematococcus pluvialis was cultivated under photoautotrophic conditions in a bubble column with fed-batch addition of nutrients, especially nitrate, and a cell number above 5 x 106 cells mL(-1) was attained after 300 h. The reduction of nutrient concentrations accompanied by dilution of the fermentation broth and an increase in the light intensity enhanced accumulation of astaxanthin. The final astaxanthin concentration of 390 mg L-1 was several times higher than ever reported. This combination of fed-batch addition of nutrients and dilution of broth for nutrient deficiency is a promising method for attainment of high cell and astaxanthin concentrations in a bubble column photobioreactor. (c) 2007 Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S1369703X07004172http://repository.hanyang.ac.kr/handle/20.500.11754/80382
ISSN
1369-703X
DOI
10.1016/j.bej.2007.11.010
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > ETC
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