Microfluidics for drug discovery and development: from target selection to product lifecycle management

Title
Microfluidics for drug discovery and development: from target selection to product lifecycle management
Author
정봉근
Keywords
ON-A-CHIP; SINGLE-CELL; PROTEIN CRYSTALLIZATION; IN-VITRO; PEPTIDE-SYNTHESIS; DRUGGABLE GENOME; NATURAL-PRODUCT; NANOLITER PLUGS; MICRO REACTOR; WHOLE-BLOOD
Issue Date
2008-01
Publisher
ELSEVIER SCI LTD
Citation
DRUG DISCOVERY TODAY, v. 13, No. 1-2, Page. 1-13
Abstract
Microfluidic technologies ability to miniaturize assays and increase experimental throughput have generated significant interest in the drug discovery and development domain. These characteristics make microfluidic systems a potentially valuable tool for many drug discovery and development applications. Here, we review the recent advances of microfluidic devices for drug discovery and development and highlight their applications in different stages of the process, including target selection, lead identification, preclinical tests, clinical trials, chemical synthesis, formulations studies and product management.
URI
https://www.sciencedirect.com/science/article/pii/S1359644607004175http://repository.hanyang.ac.kr/handle/20.500.11754/76717
ISSN
1359-6446
DOI
10.1016/j.drudis.2007.10.003
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > BIONANO ENGINEERING(생명나노공학과) > Articles
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