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dc.contributor.author성기훈-
dc.date.accessioned2018-10-11T02:10:03Z-
dc.date.available2018-10-11T02:10:03Z-
dc.date.issued2016-08-
dc.identifier.citationSENSORS AND ACTUATORS B-CHEMICAL, v. 232, Page. 514-522en_US
dc.identifier.issn0925-4005-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0925400516304634?via%3Dihub-
dc.identifier.urihttp://repository.hanyang.ac.kr/handle/20.500.11754/76450-
dc.description.abstractIn the present study, we constructed a functional paper fluidic device and evaluated its electrochemical performance by analyzing acetaminophen in the presence of ascorbic acid. The device was composed of a single-walled carbon nanotube (SWCNT) electrode and nafion-modified nitrocellulose membrane. Negatively-charged nafion was employed to build up a more negative charge on the nitrocellulose membrane, and gold nanoparticles and polyglutamic acid (AuNP-PGA) were deposited on the SWCNT electrode to enhance the electrochemical performance of the device. The device had a vertical flow format in which the sample solution flowed vertically through the paper. Using the nafion-modified nitrocellulose membrane and AuNP-PGAISWCNT film electrode as a component of the paper fluidic device, we obtained a distinguishable acetaminophen oxidation peak which was distinct from the ascorbic acid oxidation peak. The acetaminophen oxidation peak had a linear response with acetaminophen concentration, varying from 50 mu M to 300 mu M (r(2) = 0.992), which was broader than the standard drug dose range. The device exhibited a sensitivity of 13.3 mA/M and a detection limit of 15.0 mu M. The device was stable with a relative standard deviation of 3.3% (up to 2 weeks), and the reproducibility was 1.2-5.2%. Furthermore, the fabricated device accurately measured the amount of acetaminophen in pharmaceutical samples. (C) 2016 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipThis research was supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning (2008-0061891 and 2013R1A1A2054887).en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE SAen_US
dc.subjectPaper-based deviceen_US
dc.subjectAcetaminophenen_US
dc.subjectElectrochemical sensoren_US
dc.subjectCarbon nanotubeen_US
dc.subjectNanoparticleen_US
dc.subjectPolyglutamic aciden_US
dc.titleDetermination of acetaminophen using functional paper-based electrochemical devicesen_US
dc.typeArticleen_US
dc.relation.volume232-
dc.identifier.doi10.1016/j.snb.2016.03.169-
dc.relation.page514-522-
dc.relation.journalSENSORS AND ACTUATORS B-CHEMICAL-
dc.contributor.googleauthorLee, Sung Hwan-
dc.contributor.googleauthorLee, Joo Heon-
dc.contributor.googleauthorTran, Van-Khue-
dc.contributor.googleauthorKo, Euna-
dc.contributor.googleauthorPark, Chan Ho-
dc.contributor.googleauthorChung, Woo Sung-
dc.contributor.googleauthorSeong, Gi Hun-
dc.relation.code2016001030-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidghseong-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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