Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 성기훈 | - |
dc.date.accessioned | 2018-10-11T02:10:03Z | - |
dc.date.available | 2018-10-11T02:10:03Z | - |
dc.date.issued | 2016-08 | - |
dc.identifier.citation | SENSORS AND ACTUATORS B-CHEMICAL, v. 232, Page. 514-522 | en_US |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0925400516304634?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/76450 | - |
dc.description.abstract | In the present study, we constructed a functional paper fluidic device and evaluated its electrochemical performance by analyzing acetaminophen in the presence of ascorbic acid. The device was composed of a single-walled carbon nanotube (SWCNT) electrode and nafion-modified nitrocellulose membrane. Negatively-charged nafion was employed to build up a more negative charge on the nitrocellulose membrane, and gold nanoparticles and polyglutamic acid (AuNP-PGA) were deposited on the SWCNT electrode to enhance the electrochemical performance of the device. The device had a vertical flow format in which the sample solution flowed vertically through the paper. Using the nafion-modified nitrocellulose membrane and AuNP-PGAISWCNT film electrode as a component of the paper fluidic device, we obtained a distinguishable acetaminophen oxidation peak which was distinct from the ascorbic acid oxidation peak. The acetaminophen oxidation peak had a linear response with acetaminophen concentration, varying from 50 mu M to 300 mu M (r(2) = 0.992), which was broader than the standard drug dose range. The device exhibited a sensitivity of 13.3 mA/M and a detection limit of 15.0 mu M. The device was stable with a relative standard deviation of 3.3% (up to 2 weeks), and the reproducibility was 1.2-5.2%. Furthermore, the fabricated device accurately measured the amount of acetaminophen in pharmaceutical samples. (C) 2016 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | This research was supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning (2008-0061891 and 2013R1A1A2054887). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCIENCE SA | en_US |
dc.subject | Paper-based device | en_US |
dc.subject | Acetaminophen | en_US |
dc.subject | Electrochemical sensor | en_US |
dc.subject | Carbon nanotube | en_US |
dc.subject | Nanoparticle | en_US |
dc.subject | Polyglutamic acid | en_US |
dc.title | Determination of acetaminophen using functional paper-based electrochemical devices | en_US |
dc.type | Article | en_US |
dc.relation.volume | 232 | - |
dc.identifier.doi | 10.1016/j.snb.2016.03.169 | - |
dc.relation.page | 514-522 | - |
dc.relation.journal | SENSORS AND ACTUATORS B-CHEMICAL | - |
dc.contributor.googleauthor | Lee, Sung Hwan | - |
dc.contributor.googleauthor | Lee, Joo Heon | - |
dc.contributor.googleauthor | Tran, Van-Khue | - |
dc.contributor.googleauthor | Ko, Euna | - |
dc.contributor.googleauthor | Park, Chan Ho | - |
dc.contributor.googleauthor | Chung, Woo Sung | - |
dc.contributor.googleauthor | Seong, Gi Hun | - |
dc.relation.code | 2016001030 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | ghseong | - |
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