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Evaluation report on the causal association between humidifier disinfectants and lung injury

Title
Evaluation report on the causal association between humidifier disinfectants and lung injury
Author
최보율
Keywords
Causality; Humidifiers; Disinfectants; Hill’s criteria; Lung injury; Association
Issue Date
2016-08
Publisher
대한예방의학회
Citation
EPIDEMIOLOGY AND HEALTH, v. 38, Page. 6-11
Abstract
OBJECTIVES: As of November 2011, the Korean government recalled and banned humidifier disinfectants (HDs) from the market, because four case-control studies and one retrospective epidemiological study proved the association between HDs and lung injury of unknown cause. The report reviewed the causal role of HDs in lung injury based on scientific evidences. METHODS: A careful examination on the association between the HDs and lung injury was based on the criteria of causality inference by Hill and the US Surgeon General Expert Committee. RESULTS: We found that all the evidences on the causality fulfilled the criteria (strength of association, consistency,specificity, temporality, biologic gradient, plausibility, coherence, experiment, analogy, consideration of alternative explanations, and cessation of exposure), which proved the unknown cause lung injury reported in 2011 was caused by the HDs. In particular, there was no single reported case of lung injury since the ban in selling HDs in November 2011 as well as before the HDs were sold in markets. CONCLUSIONS: Although only a few epidemiological studies in Korea have evaluated the association between lung injury and the use of HDs, those studies contributed to proving the strong association between the use of the HDs and lung injury, based on scientific evidence.
URI
https://www.e-epih.org/journal/view.php?doi=10.4178/epih.e2016037http://repository.hanyang.ac.kr/handle/20.500.11754/76168
ISSN
2092-7193
DOI
10.4178/epih.e2016037
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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