Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임동우 | - |
dc.date.accessioned | 2018-09-03T09:55:12Z | - |
dc.date.available | 2018-09-03T09:55:12Z | - |
dc.date.issued | 2011-09 | - |
dc.identifier.citation | LANGMUIR, Vol.27, No.17 [2011], p10993-10999 | en_US |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://pubs.acs.org/doi/abs/10.1021/la201253z | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/74724 | - |
dc.description.abstract | Core-shell nanofibers are of great interest in the field of tissue engineering and cell biology. We fabricated porous core-shell fiber networks using an electrospinning system with a water-immersed collector. We hypothesized that the phase separation and solvent evaporation process would enable the control of the pore formation on the core-shell fiber networks. To synthesize porous core-shell fiber, networks, we used polycaprolactone (PCL) and gelatin. Quantitative analysis showed that the sizes of gelatin-PCL core-shell nanofibers increased with PCL concentrations. We also observed that the shapes of the pores created on the PCL fiber networks were elongated, whereas the gelatin-PCL core-shell fiber networks had circular pores. The surface areas of porous nanofibers were larger than those of the nonporous nanofibers due to the highly volatile solvent and phase separation process. The porous core-shell fiber network was also used as a matrix to culture various cell types, such as embryonic stem cells, breast cancer cells, and fibroblast cells. Therefore, this porous core-shell polymeric fiber network could be a potentially powerful tool for tissue engineering and biological applications. | en_US |
dc.description.sponsorship | This paper was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant Nos. 20100004869 and R11-2008-044-01002-0) and Korea Industrial Technology Foundation (KOTEF) through the Human Resource Training Project for Strategic Techonology. Institute of Bioscience and Biotechnology (KRIBB) Open Innovation Program. Muhammad Gulfam was also sponsored by 'Higher Education Commission (HEC), Govt. Of Pakistan' under the scholarship program titled : MS Level Training in Korean Universities / Industry, bearing GRE type Test Rol Number. | en_US |
dc.language.iso | en | en_US |
dc.publisher | AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA | en_US |
dc.subject | Animals | en_US |
dc.subject | Cells | en_US |
dc.subject | Cultured | en_US |
dc.subject | Electrochemistry | en_US |
dc.subject | Gelatin | en_US |
dc.subject | chemistry | en_US |
dc.subject | Humans | en_US |
dc.subject | Immunohistochemistry | en_US |
dc.subject | Materials Testing | en_US |
dc.subject | Mice | en_US |
dc.subject | Nanofibers | en_US |
dc.subject | Particle Size | en_US |
dc.title | Highly Porous Core-Shell Polymeric Fiber Network | en_US |
dc.type | Article | en_US |
dc.relation.no | 17 | - |
dc.relation.volume | 27 | - |
dc.identifier.doi | 10.1021/la201253z | - |
dc.relation.page | 10993-10999 | - |
dc.relation.journal | LANGMUIR | - |
dc.contributor.googleauthor | Gulfam, Muhammad | - |
dc.contributor.googleauthor | Lee, Jong-Min | - |
dc.contributor.googleauthor | Kim, Ji-Eun | - |
dc.contributor.googleauthor | Lim, Dong-Woo | - |
dc.contributor.googleauthor | Chung, Bong-Geun | - |
dc.contributor.googleauthor | Lee, Eun-Kyu | - |
dc.relation.code | 2011206277 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | dlim | - |
dc.identifier.researcherID | 9746456000 | - |
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