Improved motion-sensitized driven-equilibrium preparation for 3D turbo spin echo T-1 weighted imaging after gadolinium administration for the detection of brain metastases on 3T MRI
- Improved motion-sensitized driven-equilibrium preparation for 3D turbo spin echo T-1 weighted imaging after gadolinium administration for the detection of brain metastases on 3T MRI
- CONTRAST; IMSDE
- Issue Date
- BRITISH INST RADIOLOGY
- BRITISH JOURNAL OF RADIOLOGY (2016), v. 89, NO 1063, Page. 1-7
- Objective: To evaluate the clinical usefulness of an improved motion-sensitized driven-equilibrium (iMSDE) preparation for three-dimensional turbo spin echo (TSE) T-1 weighted imaging after gadolinium administration in 3.0-T MRI for the detection of brain metastases compared with conventional gradient echo (C-GRE) weighted imaging with gadolinium.
Methods: 40 patients with suspected brain metastases underwent MR studies, including two contrast-enhanced sequences, iMSDE-TSE and C-GRE. Post-enhancement images of 14 patients with suspected metastatic brain lesions were retrospectively analyzed, and comparisons between iMSDE-TSE and C-GRE were made using the Wilcoxon signed-rank test.
Results: C-GRE detected 86 metastatic lesions, whereas iMSDE-TSE detected 97, including one false-positive lesion on both sequences. 11 of 96 metastases were detected on iMSDE-TSE only. On C-GRE, 15 of 85 metastases were equivocal. There was a significant difference between C-GRE and iMSDE-TSE in terms of the number of detected lesions (p = 0.024). Notably, the interobserver agreement for diagnosing metastases and identifying non-metastases was nearly identical. Overall, iMSDE-TSE achieves higher detectability of metastatic brain lesions, especially equivocal lesions.
Conclusion: Compared with C-GRE, iMSDE-TSE detected more brain metastases, This method is especially helpful in discerning equivocal metastases.
Advances in knowledge: Previous studies have offered limited clinically useful information because they have all been preliminary studies such as comparing the contrast to-noise ratio of each sequence without evaluating iMSDE-TSE. This study, however, is unique because we evaluate the clinical usefulness of iMSDE-TSE for the detection of brain metastases, and we compare these results to C-GRE.
- 0007-1285; 1748-880X
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- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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