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Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study

Title
Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study
Author
김태환
Keywords
OF-THE-LITERATURE; POPULATION-BASED COHORT; BONE-MINERAL DENSITY; ANKYLOSING-SPONDYLITIS; RHEUMATOID-ARTHRITIS; BODY-COMPOSITION; CANCER INCIDENCE; HEART-DISEASE; RISK; RECOMMENDATIONS
Issue Date
2016-06
Publisher
BMJ PUBLISHING GROUP
Citation
ANNALS OF THE RHEUMATIC DISEASES, v. 75, NO 6, Page. 1016-1023
Abstract
Background Increased risk of some comorbidities has been reported in spondyloarthritis (SpA). Recommendations for detection/management of some of these comorbidities have been proposed, and it is known that a gap exists between these and their implementation in practice. Objective To evaluate (1) the prevalence of comorbidities and risk factors in different countries worldwide, (2) the gap between available recommendations and daily practice for management of these comorbidities and (3) the prevalence of previously unknown risk factors detected as a result of the present initiative. Methods Cross-sectional international study with 22 participating countries (from four continents), including 3984 patients with SpA according to the rheumatologist. Statistical analysis The prevalence of comorbidities (cardiovascular, infection, cancer, osteoporosis and gastrointestinal) and risk factors; percentage of patients optimally monitored for comorbidities according to available recommendations and percentage of patients for whom a risk factor was detected due to this study. Results The most frequent comorbidities were osteoporosis (13%) and gastroduodenal ulcer (11%). The most frequent risk factors were hypertension (34%), smoking (29%) and hypercholesterolaemia (27%). Substantial intercountry variability was observed for screening of comorbidities (eg, for LDL cholesterol measurement: from 8% (Taiwan) to 98% (Germany)). Systematic evaluation (eg, blood pressure (BP), cholesterol) during this study unveiled previously unknown risk factors (eg, elevated BP (14%)), emphasising the suboptimal monitoring of comorbidities. Conclusions A high prevalence of comorbidities in SpA has been shown. Rigorous application of systematic evaluation of comorbidities may permit earlier detection, which may ultimately result in an improved outcome of patients with SpA.
URI
https://ard.bmj.com/content/75/6/1016http://repository.hanyang.ac.kr/handle/20.500.11754/72606
ISSN
0003-4967; 1468-2060
DOI
10.1136/annrheumdis-2015-208174
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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