Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 주재범 | - |
dc.date.accessioned | 2018-07-16T07:37:29Z | - |
dc.date.available | 2018-07-16T07:37:29Z | - |
dc.date.issued | 2016-06 | - |
dc.identifier.citation | NANOSCALE, v. 8, NO 22, Page. 11418-11425 | en_US |
dc.identifier.issn | 2040-3364 | - |
dc.identifier.issn | 2040-3372 | - |
dc.identifier.uri | http://pubs.rsc.org/en/Content/ArticleLanding/2016/NR/C5NR07243C#!divAbstract | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/72601 | - |
dc.description.abstract | A novel surface-enhanced Raman scattering (SERS)-based lateral flow immunoassay (LFA) biosensor was developed to resolve problems associated with conventional LFA strips (e.g., limits in quantitative analysis and low sensitivity). In our SERS-based biosensor, Raman reporter-labeled hollow gold nanospheres (HGNs) were used as SERS detection probes instead of gold nanoparticles. With the proposed SERS-based LFA strip, the presence of a target antigen can be identified through a colour change in the test zone. Furthermore, highly sensitive quantitative evaluation is possible by measuring SERS signals from the test zone. To verify the feasibility of the SERS-based LFA strip platform, an immunoassay of staphylococcal enterotoxin B (SEB) was performed as a model reaction. The limit of detection (LOD) for SEB, as determined with the SERS-based LFA strip, was estimated to be 0.001 ng mL(-1). This value is approximately three orders of magnitude more sensitive than that achieved with the corresponding ELISA-based method. The proposed SERS-based LFA strip sensor shows significant potential for the rapid and sensitive detection of target markers in a simplified manner. | en_US |
dc.description.sponsorship | The National Research Foundation of Korea supported this work through grant numbers 2008-0061891 and 2009-00426. The Nano Material Technology Development Program also supported this work, through the National Research Foundation of Korea, funded by the Ministry of Science, ICT & Future Planning (2012M3A7B4035288). S.L. acknowledges the financial support (grant number 2012R1A1A2042550) from the National Research Foundation of Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | ROYAL SOC CHEMISTRY | en_US |
dc.subject | ENHANCED RAMAN-SCATTERING | en_US |
dc.subject | IMMUNOCHROMATOGRAPHIC ASSAY | en_US |
dc.subject | GOLD NANOPARTICLES | en_US |
dc.subject | VISUAL DETECTION | en_US |
dc.subject | COLLOIDAL GOLD | en_US |
dc.subject | CANCER MARKERS | en_US |
dc.subject | QUANTUM DOTS | en_US |
dc.subject | BIOSENSOR | en_US |
dc.subject | LABEL | en_US |
dc.subject | IMMUNOSENSOR | en_US |
dc.title | Application of a SERS-based lateral flow immunoassay strip for the rapid and sensitive detection of staphylococcal enterotoxin B | en_US |
dc.type | Article | en_US |
dc.relation.no | 22 | - |
dc.relation.volume | 8 | - |
dc.identifier.doi | 10.1039/c5nr07243c | - |
dc.relation.page | 11418-11425 | - |
dc.relation.journal | NANOSCALE | - |
dc.contributor.googleauthor | Hwang, Joonki | - |
dc.contributor.googleauthor | Lee, Sangyeop | - |
dc.contributor.googleauthor | Choo, Jaebum | - |
dc.relation.code | 2016000163 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | jbchoo | - |
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