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혈압강하, 어디까지 좋은가?

Title
혈압강하, 어디까지 좋은가?
Other Titles
Benefits of Intensive Blood Pressure Lowering
Author
신진호
Keywords
본태성 고혈압; 목표혈압; 진료지침; 항고혈압약제; Hypertension; Antihypertensive drugs; Practice guideline; Risk assessment
Issue Date
2016-06
Publisher
대한내과학회
Citation
대한내과학회지, v. 90, NO 6, Page. 501-506
Abstract
In general, each increase of 20/10 mmHg (systolic to diastolic) blood pressure (BP) above 115 mmHg and 75 mmHg results in a two-fold increased risk for cardiovascular complications. In addition, cerebrovascular events in association with hypertension are more frequent than myocardial infarctions in Asian populations. To prove the correlation between cardiovascular events and hypertension observed in the observational studies, BP-lowering studies should be performed to demonstrate the preventive effect on cardiovascular events. However, no randomized clinical studies to date have been able to prove the preventative effects of BP lowering in the blood pressure around 140/90 mmHg or mild hypertension. Despite the fact that many guidelines, including Joint National Committee-7 guidelines, recommend BP lowering for those ranges of blood pressure. In recent years, there have been many contradictory hypotheses about the asymmetry between the results from observational studies and clinical trials, which have led to the establishment of representative studies to set new target BPs. Such studies have proven the benefits of BP lowering closer to optimal blood pressure. Therefore, a discussion about applying these findings to patient care is needed. (Korean J Med 2016;90:501-506)
URI
http://ekjm.org/journal/view.php?doi=10.3904/kjm.2016.90.6.501http://repository.hanyang.ac.kr/handle/20.500.11754/72117
ISSN
1738-9364
DOI
https://doi.org/10.3904/kjm.2016.90.6.501
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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