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Fantasies About Stem Cell Therapy in Chronic Ischemic Stroke Patients

Title
Fantasies About Stem Cell Therapy in Chronic Ischemic Stroke Patients
Author
고성호
Keywords
CEREBRAL-ISCHEMIA; ADULT BRAIN; TOURISM; AWARENESS; RECOVERY; MEDICINE
Issue Date
2013-01
Publisher
MARY ANN LEIBERT
Citation
STEM CELLS AND DEVELOPMENT, 2013, 22(1), P.31-36
Abstract
Stem cell therapy (SCT) has been proposed for the treatment of neurological disorders. Although there is insufficient clinical evidence to support its efficacy, unproven SCTs are being performed worldwide. In this study, we investigated the perspectives and expectations of chronic ischemic stroke patients and physicians about SCTs. A total of 250 chronic ischemic stroke patients were interviewed at 4 hospitals. Structured open and closed questions about SCT for chronic stroke were asked by trained interviewers using the conventional inperson method. In addition, 250 stroke-related physicians were randomly interviewed via an e-mail questionnaire. Of the 250 patients (mean 63 years, 70% male), 121 (46%) responded that they wanted to receive SCT in spite of its unknown side effects. Around 60% of the patients anticipated physical, emotional, and psychological improvement after SCT, and 158 (63%) believed that SCT might prevent strokes. However, physicians had much lower expectations about the effectiveness of SCTs, which was not in line with patient expectations. Multivariate analysis revealed that the male gender [odds ratio (OR): 2.00, 95% confidence interval (CI): 1.10-3.64], longer disease duration (OR: 1.01, 95% CI: 1.00-1.02), higher modified Rankin Scale score (OR: 1.30, 95% CI: 1.06-1.60), and familiarity with stem cells (OR: 1.86, 95% CI: 1.10-3.15) were independently associated with wanting SCT. The major source of information about SCT was television (68%), and the most reliable source was physicians (49%). Patients have unfounded expectations that SCT will improve their functioning. Considering our finding that the major source of information on stem cells is media channels, but not the physician, to decrease patients' inappropriate exposure, doctors should make more effort to educate patients using mass media with accurate information.
URI
https://www.liebertpub.com/doi/abs/10.1089/scd.2012.0330http://repository.hanyang.ac.kr/handle/20.500.11754/69800
ISSN
1547-3287
DOI
10.1089/scd.2012.0330
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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