Histamine and TNF-a release by rat peritoneal mast cells

Title
Histamine and TNF-a release by rat peritoneal mast cells
Author
류재숙
Keywords
Trichomonas vaginalis; rat; mast cell; migration; histamine; TNF-alpha; TUMOR-NECROSIS-FACTOR; IMMUNE-RESPONSE; IN-VIVO; INFECTION; ASSOCIATION; MIGRATION; HEPARIN; MOUSE; MICE
Issue Date
2011-03
Publisher
EDP SCIENCES S A, 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE
Citation
PARASITE -PARIS- ,Vol.18 No.1 [2011],49-56
Abstract
Mast cells have been reported to be predominant in the vaginal smears of patients infected with T. vaginalis. In this study, we investigated whether T. vaginalis could induce mast cells to migrate and to produce TNF-alpha and histamine. Rat peritoneal mast cells (RPMC), a primary mast cell, were used for the study. T. vaginalis induced an increase in chemotactic migration of the mast cells toward excretory and secretory product (ESP) of T. vaginalis, and the mast cells activated with T. vaginalis showed an increased release of histamine and TNF-alpha. Therefore, mast cells may be involved in the inflammatory response caused by T. vaginalis.
URI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671398http://repository.hanyang.ac.kr/handle/20.500.11754/69582
ISSN
1252-607X
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
parasite-18-49.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE