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OVERCOMING SEGMENTATION ERRORS IN MEASUREMENTS OF MACULAR THICKNESS MADE BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Title
OVERCOMING SEGMENTATION ERRORS IN MEASUREMENTS OF MACULAR THICKNESS MADE BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY
Author
이윤정
Keywords
macular thickness measurement; overcoming segmentation errors; segmentation errors; spectral-domain optical coherence tomography; 12 radial scan protocol
Issue Date
2012-03
Publisher
Lippincott Williams & Willkins
Citation
Retina-The Journal of Retinal & Vitreous Diseases, 2012, 32(3), P.569-580
Abstract
Purpose: To assess the frequency and severity of segmentation errors in spectral-domain optical coherence tomography, and present an appropriate scan protocol for measuring macular thickness.Methods: In this study we examined 40 eyes of healthy subjects, 45 eyes with retinal pathology and 31 eyes with subretinal pathology. Patients were prospectively imaged using 12 radial scans and 3-dimensional macular cube scans by spectral-domain optical coherence tomography (3D OCT-1000; Topcon Corp., Japan) at the same sitting. Retinal segmentation errors were noted and graded using a subjective, categoric error scale to generate an error score. We compared the macular thickness measurements with and without error correction, and between the two scan protocols.Results: In this series, 63.8% of eyes (74 of 116 eyes) gave at least 1 segmentation error. Errors were more common in eyes with pathology. There was a significant difference between measurements of macular thickness with and without correcting these errors, regardless of scan protocol (P < 0.05). After error correction of both scan protocols, the macular thickness measurements obtained with the 12 radial scan protocol were equivalent to those obtained with the 3-dimensional macular cube scan protocol.Conclusion: Segmentation errors were frequent on scans obtained by spectral-domain optical coherence tomography. We recommend the 12 radial scan protocol with error correction as the standard protocol for measuring macular thickness, particularly in clinical studies. RETINA 32: 569-580, 2012
URI
https://journals.lww.com/retinajournal/pages/articleviewer.aspx?year=2012&issue=03000&article=00021&type=abstracthttp://hdl.handle.net/20.500.11754/67972
ISSN
0275-004X
DOI
10.1097/IAE.0b013e31821f5d69
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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