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dc.contributor.author최정혜-
dc.date.accessioned2018-04-16T03:46:13Z-
dc.date.available2018-04-16T03:46:13Z-
dc.date.issued2012-10-
dc.identifier.citationBIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, OCT 2012, 18(10), p1500-p1508, 9p.en_US
dc.identifier.issn1083-8791-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1083879112001383-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/67704-
dc.description.abstractAlthough younger age is associated with favorable prognosis in adults undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia (AA), other pretransplantation factors may be more important than age. We retrospectively analyzed the impact of older age on transplantation outcomes and survival in a total of 225 adult patients with AA who underwent allo-HSCT: 57 patients >40 years old (older patient group [OPG]) and 168 patients ≤40 years old (younger patient group [YPG]). Age at allo-HSCT ≤40 years, time from diagnosis to allo-HSCT ≤6 months, and matched related donor (MRD) were favorable prognostic factors in all study patients. Risk analysis of survival in the OPG showed that age >50 years was the only poor prognostic factor. Survival did not differ significantly between the YPG and patients <50 years old in the OPG. In conclusion, patients between the ages of 41 and 50 years with severe AA and MRDs should undergo allo-HSCT as early as possible to optimize survival.en_US
dc.description.sponsorshipThis work was supported by Priority Research Center Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2010-0029621).en_US
dc.language.isoenen_US
dc.publisherElsevier Science B. V. Amsterdamen_US
dc.subjectAplastic anemiaen_US
dc.subjectAllogeneic hematopoietic stem cell transplantationen_US
dc.subjectElderlyen_US
dc.titleAllogeneic Hematopoietic Stem Cell Transplant for Adults over 40 Years Old with Acquired Aplastic Anemiaen_US
dc.typeArticleen_US
dc.relation.no10-
dc.relation.volume18-
dc.identifier.doi10.1016/j.bbmt.2012.03.015-
dc.relation.page1500-1508-
dc.relation.journalBIOLOGY OF BLOOD AND MARROW TRANSPLANTATION-
dc.contributor.googleauthorKim, H.-
dc.contributor.googleauthorLee, K. H.-
dc.contributor.googleauthorYoon, S. S.-
dc.contributor.googleauthorSohn, S. K.-
dc.contributor.googleauthorJoo, Y. D.-
dc.contributor.googleauthorKim, S. H.-
dc.contributor.googleauthorKim, B. S.-
dc.contributor.googleauthorChoi, J. H.-
dc.contributor.googleauthorKwak, J. Y.-
dc.contributor.googleauthorHyun, M. S.-
dc.relation.code2012201306-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidjhcmd-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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