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Dendritic cells and regulatory T cells in atherosclerosis

Title
Dendritic cells and regulatory T cells in atherosclerosis
Author
최재훈
Keywords
atherosclerosis; dendritic cell; regulatory T cell
Issue Date
2012-10
Publisher
MOLECULES AND CELLS, OCT 2012, 34(4), p341-p347, 7p.
Citation
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Abstract
Although macrophages and other immune system cells, especially T cells, have been shown to play disease-promoting roles in atherosclerosis, less is known about the role of antigen presenting cells. Functional, immune stimulating dendritic cells (DCs) have recently been detected in aortic intima, the site of origin of atherosclerosis. We had compared DCs with macrophages in mice with experimental atherosclerosis, to clearly define cell types by developmental and functional criteria. This review summarizes recent advances in studies of DCs in humans and in mouse models of atherosclerosis, as well as providing a simple strategy to measure regulatory T (Treg) cells in the mouse aorta.
URI
https://link.springer.com/article/10.1007/s10059-012-0128-9http://hdl.handle.net/20.500.11754/67539
ISSN
1016-8478
DOI
10.1007/s10059-012-0128-9
Appears in Collections:
COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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