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dc.contributor.author계명찬-
dc.date.accessioned2018-04-16T02:30:25Z-
dc.date.available2018-04-16T02:30:25Z-
dc.date.issued2012-01-
dc.identifier.citationFood Chemistry, VOl.134, No.1 [2012], p173-179en_US
dc.identifier.issn0308-8146-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0308814612002737?via%3Dihub-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/67536-
dc.description.abstractSpirulina maxima is a blue–green alga widely used for therapeutic and health supplements and foods. This study aimed to investigate the effect of S. maxima extracts (SME) on the spermatogenesis and steroidogenesis in streptozotocin (STZ)-induced diabetic rat testes. Adult male rats were divided into control, SME (200 mg/kg bw/day, 4 weeks), STZ (single injection of 50 mg/kg bw), STZ + SME (SME 200 mg/kg bw/day, 4 weeks after STZ 50 mg/kg bw), SME + STZ (STZ 50 mg/kg bw after SME 200 mg/kg bw/day for 2 weeks) and water + STZ (STZ 50 mg/kg bw after water feeding for 2 weeks) groups. SME intake for 4 weeks significantly increased the body and testis weights, metabolic parameters, normal seminiferous tubules, Leydig cell number, testosterone levels and steroidogenic enzymes mRNA in the STZ treated rat. SME intake for 2 weeks before STZ injection also mitigated diabetic testis dysfunction. SME might have a protective effect on diabetic rat testis.en_US
dc.description.sponsorshipThe present study was supported by KRF (2009-007-4475).en_US
dc.language.isoenen_US
dc.publisherElsevier Science B.V., Amsterdam.en_US
dc.subjectSpirulina maximaen_US
dc.subjectSpermatogenesisen_US
dc.subjectSteroidogenesisen_US
dc.subjectDiabetic ratsen_US
dc.titleEffect of Spirulina maxima on spermatogenesis and steroidogenesis in streptozotocin-induced type I diabetic male ratsen_US
dc.typeArticleen_US
dc.relation.no1-
dc.relation.volume134-
dc.identifier.doi10.1016/j.foodchem.2012.02.085-
dc.relation.page173-179-
dc.relation.journalFOOD CHEMISTRY-
dc.contributor.googleauthorNah, W. H.-
dc.contributor.googleauthorKoh, I. K.-
dc.contributor.googleauthorAhn, H. S.-
dc.contributor.googleauthorKim, M. J.-
dc.contributor.googleauthorKang, H. G.-
dc.contributor.googleauthorJun, J. H.-
dc.contributor.googleauthorGye, M. C.-
dc.relation.code2012203269-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF NATURAL SCIENCES[S]-
dc.sector.departmentDEPARTMENT OF LIFE SCIENCE-
dc.identifier.pidmcgye-
dc.identifier.researcherID6701769665-
dc.identifier.orcid0000-0001-5682-3709-
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COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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