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The Pattern of Use of Oral NSAIDs with or without Co-prescription of Gastroprotective Agent for Arthritic Knee by Korean Practitioners

Title
The Pattern of Use of Oral NSAIDs with or without Co-prescription of Gastroprotective Agent for Arthritic Knee by Korean Practitioners
Author
최충혁
Keywords
Knee; Arthritis; Non-steroidal anti-inflammatory drugs; Gastroprotective agents; Co-prescription
Issue Date
2011-12
Publisher
WPRIM
Citation
Knee Surgery & Related Research, 2011, 23(4), P.203~207, 5P.
Abstract
PurposeThe aim of this study was to describe the patterns of use of non-steroidal anti-inflammatory drugs (NSAIDs) for arthritic knees in clinical practice, particularly focusing on the co-prescription of gastroprotective agents for patients with risk factors for adverse gastrointestinal (GI) events.Materials and MethodsEach cross-sectional cohort was a group of outpatients visiting 111 physicians who had prescribed NSAIDs for the patients' arthritic knees for more than three consecutive months. A self-administered questionnaire was completed by each patient and physician.ResultsNine hundred and forty five patients (48%) of the whole 1,960 patients belonged to the group with a high or very high risk for NSAID-induced gastropathy determined by northern California Health Maintenance Organization guidelines. Overall, only less than half of the patients were given co-prescription of gastroprotective agents, regardless of the presence or absence of GI symptoms and irrespective of the level of risk for NSAID-induced gastropathy.ConclusionsThe physician prescribing NSAIDs for arthritic knees should monitor any GI symptoms and the patient monitor anylevel for NSAIDinduced gastropathy, and be willing to add gastroprotective agents as necessary in order to prevent serious adverse GI events.
URI
http://www.jksrr.org/journal/view.html?doi=10.5792/ksrr.2011.23.4.203http://hdl.handle.net/20.500.11754/66853
ISSN
2234-0726
DOI
10.5792/ksrr.2011.23.4.203
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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