Infliximamb으로 치료한 건선 관절염 환자의 지염 1예

Abstract

저자들은 건선 관절염으로 NSAIDs를 사용하던 환자에서 양측 엄지손가락의 지간 관절 및 말단과 양측 발의 지간 관절을 대칭적으로 침범한 건선 관절염에 의한 지염을 관찰하였고, infliximab을 투여하여 치료한 예를 경험하여 이런 예가 국내에서 보고가 없었으므로 이를 보고한다. 또한 본 환자에서는 단순 방사선 사진에서의 변화가 뚜렷하지 않아 bone scan 중 blood pool image로의 추적관찰이 유용했다.Dactylitis is a hallmark feature of psoriatic arthritis. It is usually managed with non-steroidal anti-inflammatory drugs and oral corticosteroids. Some cases have been treated successfully with intravenous corticosteroids or some disease-modifying antirheumatic drugs. Recently, inflximab has been reported as an effective treatment for dactylitis that is resistant to conventional treatment. This report describes a 37-year-old man with psoriatic arthritis who had multiple dactylitis on both thumbs and great toes. He was resistant to conventional treatment but was effectively treated with infliximab. This report highlights the effectiveness of infliximab for dactylitis, and the usefulness of blood pool imaging from bone scans as a method for determining treatment response. (Korean J Med 2011;80:S310-S313)