Claudin-11 expression increased in spermatogenic defect in human testes
- Title
- Claudin-11 expression increased in spermatogenic defect in human testes
- Author
- 계명찬
- Keywords
- Claudin-11; human; Sertoli cells; testis; tight junction
- Issue Date
- 2011-01
- Publisher
- Elsevier Science B.V., Amsterdam.
- Citation
- FERTILITY AND STERILITY 권: 95 호: 1 페이지: 385-388
- Abstract
- Expression of claudin-11, which builds up blood-testis barrier (BTB), was increased in decreased spermatogenesis, including in hypospermatogenesis, spermatocytic and maturation arrest, and Sertoli cell only (SCO) testes. Increased claudin-11 immunoreactivity was observed at the inter-Sertoli tight junctions in maturation arrest and in the cytoplasm of Sertoli cells in SCO. The late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the BTB in the human testis. (Fertil Steril (R) 2011;95:385-8. (C) 2011 by American Society for Reproductive Medicine.)
- URI
- http://www.fertstert.org/article/S0015-0282(10)02411-8/fulltexthttp://hdl.handle.net/20.500.11754/66117
- ISSN
- 0015-0282; 1556-5653
- DOI
- 10.1016/j.fertnstert.2010.08.023
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML