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Cognitive impairment, depression, comorbidity of the two and associated factors among the early sixties in a rural Korean community

Title
Cognitive impairment, depression, comorbidity of the two and associated factors among the early sixties in a rural Korean community
Author
박보영
Keywords
Age Factors; Comorbidity; Cross-Sectional Studies; Depression; epidemiology; Depressive Disorder; Female; Humans; Male; Middle Aged; Odds Ratio; Republic of Korea; Risk Factors; Rural Population; Socioeconomic Factors
Issue Date
2013-11
Publisher
PUBLIC LIBRARY SCIENCE
Citation
PLOS ONE, 8(11), e79460
Abstract
This study was conducted to investigate the prevalence of cognitive impairment, depression, and comorbidity of the two conditions and related factors in subjects aged in early 60s. This cross-sectional study included 3,174 inhabitants aged 60-64 years old in a rural area of Korea. Cognitive function was evaluated by the Korean version of the Mini-Mental State Examination (MMSE-K), and depression was measured using the short form of the Geriatric Depression Scale (GDS-15). The overall prevalence of cognitive impairment (MMSE-K <= 24) was 17.4%, that of depression was 26.0% (GDS-15 >= 8), and the comorbidity was 7.1%. Female gender, living with one housemate, and high GDS-15 score were significantly associated with increased cognitive impairment. Employment status and more years of schooling were associated with a decreased probability of cognitive impairment. Increased depression was significantly associated with bereavement and receiving benefits from the Medical Aid Program. Employed status, more years of schooling, and higher MMSE-K scores were significantly associated with decreased depression. The risk of comorbidity was associated with bereavement and receipt of Medical Aid benefits (odds ratio[OR], 1.85; 95% confidence interval[CI], 1.26-2.71; OR, 5.02; 95% CI, 2.37-10.63; respectively). Employment and more years of schooling were associated with a lower risk of comorbidity (OR, 0.46; 95% CI, 0.34-0.62, P-trend <0.01). The correlated factors for cognitive impairment, depression, and comorbidity of the two conditions were similar, and employment status and years of schooling were associated with all three conditions.
URI
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079460http://hdl.handle.net/20.500.11754/55363
ISSN
1932-6203
DOI
10.1371/journal.pone.0079460
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > ETC
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