Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이민형 | - |
dc.date.accessioned | 2018-04-02T07:39:49Z | - |
dc.date.available | 2018-04-02T07:39:49Z | - |
dc.date.issued | 2011-11 | - |
dc.identifier.citation | Journal of Controlled Release, 2011, 152(1), P.151-152 | en_US |
dc.identifier.issn | 0168-3659 | - |
dc.identifier.issn | 1873-4995 | - |
dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0168365911006705 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/54936 | - |
dc.description.abstract | R3V6 peptides, which were composed of 3 arginines and 6 valines, formed self-assembled micelles in an aqueous solution. To improve the transfection efficiency of the R3V6 peptide micelles, a hydrophobic drug, dexamethasone was loaded into the core of the R3V6 peptide micelles. In vitro transfection assay showed that the dexamethasone-loaded R3V6 peptide micelles deliver DNA more effectively than the R3V6 micelles. In addition, the dexamethasone-loaded R3V6 micelles reduced the IL-6 levels in the lipopolysaccharide (LPS) activated macrophage cells. | en_US |
dc.description.sponsorship | This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (20100002119). | en_US |
dc.language.iso | en | en_US |
dc.publisher | Medline | en_US |
dc.subject | Amphiphile | en_US |
dc.subject | Micelle | en_US |
dc.subject | Plasmid | en_US |
dc.subject | DNA delivery | en_US |
dc.subject | Dexamethasone | en_US |
dc.title | Dexamethasone loaded r3v6 peptide micelles for gene delivery | en_US |
dc.type | Article | en_US |
dc.relation.volume | 152 | - |
dc.identifier.doi | 10.1016/j.jconrel.2011.08.056 | - |
dc.relation.page | 151-152 | - |
dc.relation.journal | JOURNAL OF CONTROLLED RELEASE | - |
dc.contributor.googleauthor | Lee, Jiyoung | - |
dc.contributor.googleauthor | Hyun, Hyesun | - |
dc.contributor.googleauthor | Kim, Hyun Ah | - |
dc.contributor.googleauthor | Lee, Minhyung | - |
dc.contributor.googleauthor | 이지영 | - |
dc.contributor.googleauthor | 현희석 | - |
dc.contributor.googleauthor | 김현아 | - |
dc.contributor.googleauthor | 이민형 | - |
dc.relation.code | 2011204927 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF BIOENGINEERING | - |
dc.identifier.pid | minhyung | - |
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