Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김용주 | - |
dc.date.accessioned | 2018-03-29T02:37:24Z | - |
dc.date.available | 2018-03-29T02:37:24Z | - |
dc.date.issued | 2014-12 | - |
dc.identifier.citation | Pediatric Gastroenterology, Hepatology & Nutrition, 17(4), p.232-238 | en_US |
dc.identifier.issn | 2234-8646 | - |
dc.identifier.uri | https://synapse.koreamed.org/DOIx.php?id=10.5223/pghn.2014.17.4.232 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/53596 | - |
dc.description.abstract | Purpose: This study investigated the clinical presentations of symptomatic Clostridium difficile infection (CDI) in children. Methods: We reviewed the medical records of 43 children aged <20 years who showed either positive C. difficileculture or C. difficile toxin test results between June 2010 and April 2014. Results: Of the 43 patients (mean age 6.7 years), 22 were boys. Sixteen patients (37.2%) showed both positive C. difficile culture and toxin test results. Seventeen out of 43 children (39.5%) had preexisting gastrointestinal dis-eases, and 26 children had other medical conditions that were risk factors for CDI. Twenty-eight children had a history of antibiotic treatment for >3 days, and the most frequently prescribed antibiotic was amoxicillin-clavulanate (35.7%). Twenty-eight patients were diagnosed with CDI despite taking probiotic supplements, most commonly Lactobacillus acidophilus (53.6%). The most common symptom was diarrhea (72.1%) at the time CDI was diagnosed. C. difficilewas eradicated in 11 patients (25.6%) after treatment with oral metronidazole for 10-14 days, and in the two patients (4.6%) who required two courses of oral metronidazole. Sixteen patients (37.2%) showed clinical improvement with-out any treatment. Conclusion: This study showed the various clinical characteristics of CDI in children and that preexisting clinical conditions favored the development of CDI. In addition, CDI was found to occur in a number of patients even after probiotic prophylaxis given in conjunction with antibiotic therapy. | en_US |
dc.language.iso | en | en_US |
dc.publisher | The Korean Society of Pediatric Gastroenterology | en_US |
dc.subject | Clostridium difficile | en_US |
dc.subject | Probiotics | en_US |
dc.subject | Child | en_US |
dc.subject | Diarrhea | en_US |
dc.title | Clinical Characteristics of Symptomatic Clostridium difficile Infection in Children: Conditions as Infection Risks and Whether Probiotics Is Effective | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 17 | - |
dc.identifier.doi | 10.5223/pghn.2014.17.4.232 | - |
dc.relation.page | 232-238 | - |
dc.relation.journal | Pediatric Gastroenterology, Hepatology & Nutrition | - |
dc.contributor.googleauthor | Na, Jae Yoon | - |
dc.contributor.googleauthor | Park, Jong Mo | - |
dc.contributor.googleauthor | Lee, Kyung Suk | - |
dc.contributor.googleauthor | Kang, Jung Oak | - |
dc.contributor.googleauthor | Oh, Sung Hee | - |
dc.contributor.googleauthor | Kim, Yong Joo | - |
dc.relation.code | 2014001313 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kyjoo | - |
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