중심정맥도관관련 혈류감염의 신속한 진단을 위한 실시간 다중핵산증폭검사의 유용성 평가
- Title
- 중심정맥도관관련 혈류감염의 신속한 진단을 위한 실시간 다중핵산증폭검사의 유용성 평가
- Author
- 김태형
- Keywords
- SeptiFast test; Catheter-related infections; Blood culture
- Issue Date
- 2011-03
- Publisher
- 대한감염학회
- Citation
- Infection and Chemotherapy, 2011, 43(3), P.240-244
- Abstract
- Background: The study evaluated the clinical efficacy of a multi-parameter realtime polymerase chain reaction (PCR) test for patients with central venous catheterrelated bloodstream infection (CRBSI). Materials and Methods: Thirty five patients suspected to have CRBSI were enrolled. The SeptiFast™ (SF) multi-parameter real-time PCR test (Roche Diagnostics, Germany) and blood culture were performed and results were compared. Results: The turn-around time for the SF test and blood culture was 32.6±28.9 hours and 115.8±23.5 hours, respectively. Among the 70 blood samples, the positive rates of SF test and blood culture were 34.3% and 27.1%, respectively, and the agreement rate was 62.9%. Gram-positive bacteria were detected in 10 patients with blood culture and 11 patients with SF test. Gram-negative bacteria were detected in one patient with a blood culture and in seven patients with SF test. Candida was not detected in blood culture but was detected in two patients by the SF test. Conclusions: SF test was faster and more sensitive for the detection of blood pathogens than blood culture. It provides a more sensitive detection of gramnegative and Candida in blood than does blood culture testing.
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.3947/ic.2011.43.3.240
- DOI
- 10.3947/ic.2011.43.3.240
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
- ic-43-240.pdfDownload
- Export
- RIS (EndNote)
- XLS (Excel)
- XML